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| Product | Description | |
|---|---|---|
| Bafilomycin a1 | Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 88899-55-2. Molecular formula: C35H58O9. Mole weight: 622.83. Purity: >98 %. Product ID: ACM88899552. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Bafilomycin A1 | Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H + -ATPase ( V-ATPase ) with IC 50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: BafA1. CAS No. 88899-55-2. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-100558. |  |
| Bafilomycin A1 | Bafilomycin A1 Inhibitor. Uses: Scientific use. Product Category: T6740. CAS No. 88899-55-2. |  |
| Bafilomycin A1 | It is produced by the strain of Streptomyces griseus ssp. sulphurus TU 1022 and Str. griseus TU 2437. Bafilomycin A1 is a vacuolar H+-ATPase inhibitor with IC50 of 0.44 nM. It can inhibit the growth of gram-positive bacteria, negative bacteria, fungi, yeast and protozoa, and has the effects of insect killing, nematode killing and immunosuppression. Synonyms: NSC 381866; NSC-381866; NSC381866; Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 8-hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-; (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one; Hygrolidin, 21-O-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-; (-)-Bafilomycin A1; Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 8-hydroxy-16-[2-hydroxy-1-methyl-3-[tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyl-, [7R-[3Z,5E,7R*,8S*,9S*,11E,13E,15S*,16R*[1S*,2R*,3S*(2R*,4R*,5S*,6R*)]]]-. Grade: ≥95% by HPLC. CAS No. 88899-55-2. Molecular formula: C35H58O9. Mole weight: 622.83. |  |
| Bafilomycin A1 (NSC381866) | Bafilomycin A1 is a member of a potent family of macrocyclic lactones with a broad spectrum of biological activity including activity against bacteria, yeast, fungi, nematodes, insects and antitumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase. Related to: Bafilomycin B1, Bafilomycin C1, Concanamycin A.Source:Streptomyces griseus. Group: Biochemicals. Alternative Names: 21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-hygrolidin Oxacyclohexadecane, hygrolidin deriv.; (-)-Bafilomycin A1; NSC 381866; [7R-[3Z, 5E, 7R*, 8S*, 9S*, 11E, 13E, 15S*, 16R*[1S*, 2R*, 3S*(2R*, 4R*, 5S*, 6R*)]]]-8-Hydroxy-16-[2-hydroxy-1-methyl-3-[tetrahydro-2, 4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3, 15-dimethoxy-5, 7, 9, 11-tetramethyl-oxacyclohexadeca-3, 5, 11, 13-tetraen-2-one. Grades: Highly Purified. CAS No. 88899-55-2. Pack Sizes: 100ug, 1mg. Molecular Formula: C35H58O9, Molecular Weight: 622.8. US Biological Life Sciences. |  Worldwide |
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