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| Product | Description | |
|---|---|---|
| 9-Phenanthrol | 9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC 50 of 17 μM. 9-Phenanthrol has no inhibitory activity on TRPM5, TRPC6, and CFTR. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9-Hydroxyphenanthrene; NSC 50554. CAS No. 484-17-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-108457. |  |
| 9-Phenanthrol | 9-Phenanthrol, a cell permeable hydroxytricyclic derivative, functions as a selective inhibitor of TRPM4 (IC50 = 20 μM in HEK293 cells) and exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM respectively). 9-Phenanthrol was used to investigate C K-edge and O K-edge near-edge X-ray absorption fine structure (NEXAFS) spectra of single-wall carbon nanotubes. Uses: Protein kinase inhibitors. Synonyms: phenanthren-9-ol. CAS No. 484-17-3. Molecular formula: C14H10O. Mole weight: 194.23. |  |
| 9-Phenanthrol | A metabolite of Phenanthrene. Group: Biochemicals. Alternative Names: 9-Phenanthrenol; 9-Hydroxyphenanthrene; NSC 50554. Grades: Highly Purified. CAS No. 484-17-3. Pack Sizes: 10mg, 100mg. Molecular Formula: C??H??O, Melting Point: 143-146°C. US Biological Life Sciences. |  Worldwide |
| 9-Phenanthrol, TRPM4 Inhibitor (Phenanthren-9-ol, 9-Hydroxyphenanthrene) | A cell permeable hydroxytricyclic derivative that acts as a specific and reversible inhibitor of transient receptor potential melastatin 4 (TRPM4) (IC50=20uM in HEK293 cells). Does not affect TRPM5 and cystic fibrosis transmembrane conductance regulators (CFTR) channels. Decreases the occurrence of early after depolarizations (EAD) and exhibits an anti-arrhythmic effect that is independent of the action of protein kinase A. Shown to abolish nMDA-induced burst firing in dopaminergic neurons. Does not affect K+ currents at ~10uM, but at higher concentration (~100uM) it reversibly reduces K+ currents. Group: Biochemicals. Grades: Highly Purified. CAS No. 484-17-3. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
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