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| Product | Description | |
|---|---|---|
| Xaliproden hydrochloride | Xaliproden hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 90494-79-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Xaliproden hydrochloride | Xaliproden hydrochloride is a potent, selective and orally active 5-HT1A receptor agonist with a high affinity for 5-HT1A specific binding sites in the rat hippocampus (IC50 = 3 nM). It is also a selective dopamine D2 receptor antagonist with moderate affinity (IC50 = 0.1-1 μM). It has antidepressant and anti-anxiety effects, and may have therapeutic potential in neurodegenerative diseases research. Uses: Serotonin 5-ht1 receptor agonists. Synonyms: SR57746A; SR57746 hydrochloride; 1-[2-(2-Naphthyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride; 1,2,3,6-Tetrahydro-1-[2-(2-naphthalenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]pyridine hydrochloride. Grades: ≥99%. CAS No. 90494-79-4. Molecular formula: C24H23ClF3N. Mole weight: 417.89. |  |
| Xaliproden hydrochloride | Xaliproden hydrochloride (SR57746A) is a potent, selective and orally active agonist of 5-HT 1A receptor , shows a high affinity for 5-HT 1A specific binding sites in the rat hippocampus ( IC 50 =3 nM). Xaliproden hydrochloride is also a selective antagonist of dopamine D 2 receptor , has moderate affinity ( IC 50 =0.1-1 μM). Xaliproden hydrochloride exhibits anti-depression and anti-anxiety effects, and it may possess therapeutic potential for the research of neurodegenerative diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR57746A; SR57746 hydrochloride. CAS No. 90494-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14604. |  |
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