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| Product | Description | |
|---|---|---|
| A 83-01 | A 83-01. Group: Biochemicals. Alternative Names: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide. Grades: Highly Purified. CAS No. 909910-43-6. Pack Sizes: 10mg. Molecular Formula: C25H19N5S, Molecular Weight: 421.52. US Biological Life Sciences. |  Worldwide |
| A 83-01 | A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase , type I nodal receptor ALK4 and type I nodal receptor ALK7 , with IC 50 s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5 , ALK4 and ALK7 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 909910-43-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10432. |  |
| A-83-01 | A 83-01 is an inhibitor of TGF-β type I receptor kinase (ALK5), activin type IB receptor (ALK4), and nodal type I receptor (ALK7) (IC50s = 12, 45, and 7.5 nM, respectively). It blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition. Synonyms: A8301; A 8301; A-8301. Grades: 98%. CAS No. 909910-43-6. Molecular formula: C25H19N5S. Mole weight: 421.52. |  |
| A83-01 | A83-01 Inhibitor. Uses: Scientific use. Product Category: T3031. CAS No. 909910-43-6. |  |
| A 83-01 (3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide) | A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5nM respectively). Blocks. Group: Biochemicals. Alternative Names: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide. Grades: Highly Purified. CAS No. 909910-43-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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