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Tertiapin-Q Quick inquiry Where to buy Suppliers range | Tertiapin-Q, a derivative of the bee venom toxin tertiapin, is a high affinity blocker of inward-rectifier K+ channels. Tertiapin-Q binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels (Ki = 1.3 and 13.3 nM, respectively) with selectivity over Kir2.1 channels. Synonyms: L-Lysinamide, L-alanyl-L-leucyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-asparaginyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-histidyl-L-glutaminyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-lysyl-L-cysteinylglycyl-L-lysyl-, cyclic (3?14),(5?18)-bis(disulfide); Tertiapin Q; L-alanyl-L-leucyl-L-cysteinyl-L-asparagyl-L-cysteinyl-L-asparagyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-histidyl-L-glutaminyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-lysyl-L-cysteinyl-glycyl-L-lysyl-L-lysinamide (3->14),(5->18)-bis(disulfide); H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 (Disulfide bridge: Cys3-Cys14, Cys5-Cys18). Grades: ≥95%. CAS No. 910044-56-3. Molecular formula: C106H175N35O24S4. Mole weight: 2452.01. | |
Tertiapin-Q Quick inquiry Where to buy Suppliers range | Tertiapin Q is a stable derivative of the bee venom toxin tertiapin. It is a high affinity blocker for inward-rectifier K+ channels that binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with high affinity (Ki values are 1.3 and 13.3 nM respectively). Uses: Peptide Inhibitors. CAS No. 910044-56-3. Product ID: R1101. |