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| Product | Description | |
|---|---|---|
| Veliparib | ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo. Group: Biochemicals. Alternative Names: 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide; A 861695; ABT 888. Grades: Purified. CAS No. 912444-00-9. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Veliparib | Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. In HCT-116 and HT-29 cell lines, the ability of ABT-888 to synergize the effect of the anti-cancer agents, SN38 or oxaliplatin, was determined using the SRB assay. PARP activity was significantly reduced in samples treated with SN38 in combination with ABT-888 (>4 fold at 24 h). Uses: For research used only. Synonyms: (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide; ABT888; ABT-888; ABT 888; Veliparib. Grades: 0.99. CAS No. 912444-00-9. Molecular formula: C13H16N4O. Mole weight: 244.298. |  |
| Veliparib | Veliparib (ABT-888) is a potent PARP inhibitor, inhibiting PARP1 and PARP2 with K i s of 5.2 and 2.9 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-888. CAS No. 912444-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10129. |  |
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