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HA-1004 monohydrochloride HA-1004 is a potent inhibitor of PKA and PKG with Ki values of 2.3 and 1.4 μM, respectively. It also inhibits PKC and calcium channel protein. HA-1004 was studied as a relaxant for rabbit aortic strips contracted by various agonists, suggesting its potential use for vasorelaxation. Uses: A novel calcium antagonist and vasodilator with no effect on cardiac function. Synonyms: 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, hydrochloride (1:1); 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, monohydrochloride; HA 1004 hydrochloride; N-(2-Guanidinoethyl)-5-isoquinolinesulfonamide Hydrochloride; N-[2-[(Aminoiminomethyl)amino]ethyl]-5-isoquinolinesulfonamide Monohydrochloride. Grade: 95%. CAS No. 92564-34-6. Molecular formula: C12H15N5O2S.HCl. Mole weight: 329.81. BOC Sciences 8
Protein Kinase Inhibitor HA1004 (PKI) (N- (2-guanidinoethyl ] -5-isoquinolinesulfonamid e dihydrochloride) Calcium antagonist and vasodilator. Does not affect on cardiac function. Group: Biochemicals. Alternative Names: N- (2-guanidinoethyl ] -5-isoquinolinesulfonamid e dihydrochloride. Grades: Molecular Biology Grade. CAS No. 92564-34-6. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 1
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