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| Product | Description | |
|---|---|---|
| BIX 01294 | Selective and cell permeable G9a histone lysine methyltransferase (HMTase) inhibitor. Pluripotent stem cell inducer. Group: Biochemicals. Alternative Names: 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-4-quinazolinamine. Grades: Highly Purified. CAS No. 935693-62-2. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C28H38N6O2. US Biological Life Sciences. |  Worldwide |
| BIX-01294 | BIX-01294, a diazepin-quinazolinamine derivative, is a selective inhibitor of G9a histone methyl transferase (G9a HMTase) that impairs G9a HMTase and generation of H3K9me2 in vitro. It does not compete with cofactor S-adenosyl-methionine. It enhances reprogramming efficiency of neural progenitor cells to the same levels as when four transcription factors (Oct4, Klf4, Sox2 and c-Myc) were introduced to somatic cells for generation of induced pluripotent stem cells. It may replace the requirement for ectopic OCT4 (POU5F1) and cMyc respectively in pluripotent stem cell induction (iPS). Synonyms: BIX-01294; BIX 01294; BIX01294. Grades: >98%. CAS No. 935693-62-2. Molecular formula: C28H38N6O2. Mole weight: 490.64. |  |
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