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NIH-12848 NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NIH-12848; NIH 12848; NIH12848, NCGC00012848-02. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 959551-10-1. Molecular formula: C20H14F3N3S. Mole weight: 385.41. Purity: >98%. IUPACName: N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine. Canonical SMILES: FC(F)(F)C(C=CC=C1)=C1C2=NC3=CC=CC=C3C(NCC4=CC=CS4)=N2. Product ID: ACM959551101. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
NIH-12848 NIH-12848 is putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor (IC50 = 1 μM) but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. Synonyms: N-(thiophen-2-ylmethyl)-2-[2-(trifluoromethyl)phenyl]quinazolin-4-amine; NCGC00012848-02; NIH-12848; NIH 12848; NIH12848, NCGC00012848-02. CAS No. 959551-10-1. Molecular formula: C20H14F3N3S. Mole weight: 385.41. BOC Sciences 9

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