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| Product | Description | |
|---|---|---|
| Orlistat | Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolem ic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN). Anti-proliferative. Causes cell cycle arrest at G1 phase. Apoptosis inducer through caspase-3 activation. Sn-1-selective-diacylglycerol lipases alpha (DAGLalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways. Source:Synthetic. Originally isolated from Streptomyces sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 96829-58-2. Pack Sizes: 50mg, 250mg. Molecular Formula: C29H53NO5. US Biological Life Sciences. |  Worldwide |
| Orlistat | Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase ( FASN ), is used orally for long-term research of obesity [1]. Anti-atherosclerotic effect [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tetrahydrolipstatin; Ro-18-0647. CAS No. 96829-58-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0218. |  |
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