Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| A 839977 | A 839977. Group: Biochemicals. Grades: Purified. CAS No. 870061-27-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| A 839977 | A-839977 is a novel and selective P2X7 antagonist. It blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors with IC50 values 20, 42 and 150 nM respectively. It also potently blocked agonist-evoked YO-PRO uptake and IL-1beta release from differentiated human THP-1 cells. It also produced robust antihyperalgesia in the CFA model of inflammatory pain in wild-type mice. It has been exhibited to reduce CFA-induced thermal hyperalgesia in a dose-dependent fashion with the ED50 value of 100μmol/kg. Synonyms: 1-(2,3-Dichlorophenyl)-N-[[2-[(pyridin-2-yl)oxy]phenyl]methyl]-1H-tetrazol-5-amine. Grades: >98 %. CAS No. 870061-27-1. Molecular formula: C19H14Cl2N6O. Mole weight: 413.26. |  |
Our database is helping our users find suppliers everyday.
