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| Product | Description | |
|---|---|---|
| A-1210477 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| A-1210477 | A-1210477 is a potent and selective inhibitor of MCL-1 with a Ki of 0.45 nM[1]. A-1210477 specifically binds MCL-1 and promotes apoptosis of cancer cells in an MCL-1-dependent manner[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1668553-26-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12468. |  |
| A-1210477 | A-1210477 is a potent and selective MCL-1 inhibitor with Ki and IC50 of 0.454 nM and 26.2 nM, respectively, >100-fold selectivity over other Bcl-2 family members. Synonyms: A 1210477; A1210477; Abbvie Mcl-1 Inhibitor; 7-(5-((4-(4-(N,N-Dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid. Grades: 98%. CAS No. 1668553-26-1. Molecular formula: C46H55N7O7S. Mole weight: 850.04. |  |
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