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| Product | Description | |
|---|---|---|
| Abexinostat | Abexinostat, also known as PCI-24781 or CRA-024781, is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. Abexinostat inhibits several isoforms of HDAC, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling. Synonyms: CRA-024781; CRA 024781; CRA024781; PCI-24781; PCI24781; PCI 24781. Grades: 98%. CAS No. 783355-60-2. Molecular formula: C21H23N3O5. Mole weight: 397.431. |  |
| Abexinostat | Abexinostat (CRA 024781) is a novel pan- HDAC inhibitor mostly targeting HDAC1 with K i of 7 nM. Abexinostat also inhibits metallo-β-lactamase domain-containing protein?2 ( MBLAC2 ) hydrolase activity with an EC 50 below 10 nM [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CRA 024781; PCI-24781. CAS No. 783355-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10990. |  |
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