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| Product | Description | |
|---|---|---|
| Abrocitinib | Abrocitinib is a seletive JAK1 inhibitor with IC50 value of 29 nM. Abrocitinib has been investigated for the treatment of plaque psoriasis. Synonyms: PF-04965842; N-[3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide. Grades: >98%. CAS No. 1622902-68-4. Molecular formula: C14H21N5O2S. Mole weight: 323.415. |  |
| Abrocitinib | Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC 50 s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 ( IC 50 , 1.253 μM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04965842. CAS No. 1622902-68-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107429. |  |
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