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Acesulfamepotassium is a synthetic sweetener. Long-term use of Acesulfamepotassium can affect cognitive function, possibly by altering the neurometabolic functions in mice. Acesulfamepotassium can suppress autophagic degradation of PD-L1 in RIL-175 and SK-Hep1 cells through the ERK1/2-mTORC1-ULK1 pathway, which may be related to immune evasion in cancer cells. Acesulfamepotassium can be used in research on neurological diseases, metabolic disorders, cancer, and immune evasion [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 55589-62-3. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0195.
AcesulfamePotassium
AcesulfamePotassium. CAS No. 55589-62-3. Product ID: PE-0484. Molecular formula: C4H4KNO4S. Mole weight: 201.24. Category: Sweetening agent. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; AcesulfamePotassium; Sweeteners Excipients; Sweetening agent; C4H4KNO4S; 55589-62-3; 55589-62-3. UNII: NA. Chemical Name: 6-Methyl-1, 2, 3-oxathiazin-4(3H)-one-2, 2-dioxide potassium salt. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: Oral preparations. Stability and Storage Conditions: Acetylsul panpotassium has good stability. Stored in bulk at room temperature for many years without signs of decomposition. The sweetness of aqueous solution (pH 3.0 - 3.5, 20°C) did not decrease for about two years. Although some decomposition after storage at 40°C for several months, it has good stability at temperature rise. Neither sterilization nor pasteurization affected the sweetness of acetylsulpanpotassium. Bulk products should be stored in airtight containers in a dry place. Source and Preparation: Acetylsul panpotassium is synthesized from tert-butyl acetoacetate and fluorosulfonyl isocyanate. The resulting product is converted to fluorosulfonyl acetoacetamide and cyclized into dioxythiazone cyclization in the presence of potassium hydroxide. Because this compound is strongly acidic, it can directly form potassium salt. Another route for the synthesis of acetylsulfamide be
AcesulfamePotassium
AcesulfamePotassium is used as a potent sweetener in cosmetics, foods and beverage products, table-top sweeteners, vitamins and pharmaceutical preparations, including powder mixtures, tablets and liquid products. Synonyms: Acesulfame K; ace K; acesulfamum kalicum; E950; 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4(3H)-one-2,2-dioxide potassium salt; potassium 6-methyl-2,2-dioxo-oxathiazin-4-olate; Sunett; Sweet One; 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-Dioxide Potassium Salt; 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-Dioxide Potassium Salt; Otizon; PotassiumAcesulfame. Grades: ≥97%. CAS No. 55589-62-3. Molecular formula: C4H4KNO4S. Mole weight: 201.24.
AcesulfamePotassium
New generation', heat-stable sweetener that has not been suspected to cause cancer nor be genotoxic. Allelic variation of the Tas1r3 gene affects behavioral taste responses to this molecule, suggesting that it is a T1R3 receptor ligand. Group: Biochemicals. Alternative Names: 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-Dioxide Potassium Salt; 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-Dioxide Potassium Salt; E 950; Otizon; PotassiumAcesulfame; Sunett; Sunnett; Sweet One. Grades: Highly Purified. CAS No. 55589-62-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
AcesulfamePotassium EP Impurity A (Acetoacetamide)
AcesulfamePotassium EP Impurity A (Acetoacetamide). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5977-14-0 (keto form); 120166-77-0 (enol form); 3-hydroxybut-2-enamide compound with 3-oxobutanamide (1:1). Molecular Formula: C4H7NO2. Mole Weight: 101.10. Catalog: APB03130.
AcesulfamePotassium USP
AcesulfamePotassium USP. WHO-GMP. Acesulfame-Potassium. CAS 55589-62-3
International
Acesulfame-[d4] Potassium Salt
Acesulfame-[d4] Potassium Salt is a labelled version of AcesulfamePotassium. Acesulfamepotassium is a non-nutritive sweetener. Synonyms: 6-Methyl-1,2,3-oxathiazin-4(3H)-one-d4 2,2-Dioxide Potassium Salt; Acesulfam H-d4 Potassium Salt; 3,4-Dihydro-6-methyl-1,2,3-oxathiazin-4-one-d4 2,2-Dioxide Potassium Salt. CAS No. 1623054-53-4. Molecular formula: C4D4KNO4S. Mole weight: 205.27.
Acesulfame-d4 Potassium Salt
New generation', heat-stable sweetener that has not been suspected to cause cancer nor be genotoxic. Allelic variation of the Tas1r3 gene affects behavioral taste responses to this molecule, suggesting that it is a T1R3 receptor ligand. Group: Biochemicals. Alternative Names: 6-Methyl-1,2,3-oxathiazin-4(3H)-one-d4 2,2-Dioxide Potassium Salt; Acesulfam H-d4 Potassium Salt; 3,4-Dihydro-6-methyl-1,2,3-oxathiazin-4-one-d4 2,2-Dioxide Potassium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Acesulfame-D4 Potassium Salt
Acesulfame-D4 Potassium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1623054-53-4. Molecular Formula: C4D4KNO4S. Mole Weight: 205.26. Catalog: APB1623054534.
Acesulfame K (Potassium) BP
Acesulfame K (Potassium) BP. CAS No. 55589-62-3. Molecular formula: C4H4KNO4S.
5-Chloro Acesulfame
5-Chloro Acesulfame. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-Chloro-6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide, Acesulfam Potassium Imp. B (EP). CAS No. 72827-08-8. Pack Sizes: 10MG. IUPAC Name: 5-chloro-6-methyl-2,2-dioxooxathiazin-4-one. Molecular Formula: C4H4ClNO4S. Mole Weight: 197.60. Catalog: APS72827088. SMILES: CC1=C(Cl)C(=O)NS(=O)(=O)O1. Format: Neat. Shipping: Room Temperature.