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BIO-acetoxime (BIA) is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. BIO-acetoxime has anticonvulsant and anti-infection activity. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 667463-85-6. Molecular formula: C18H12BrN3O3. Mole weight: C18H12BrN3O3. Purity: >98 %. Product ID: ACM667463856. Alfa Chemistry ISO 9001:2015 Certified.
BIO-acetoxime
BIO-acetoxime. Group: Biochemicals. Grades: Purified. CAS No. 667463-85-6. Pack Sizes: 1mg, 10mg. US Biological Life Sciences.
Worldwide
BIO-acetoxime
BIO-acetoxime is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. It shows >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B. It has anticonvulsant and anti-infection activity. Synonyms: BIA; GSK-3 Inhibitor X; (2'Z,3'E)-6-Bromoindirubin-3'-acetoxime; (3Z)-3-[(3E)-3-(Acetoxyimino)-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 3-[(3E)-3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-, (3Z)-; 6-Bromoindirubin acetoxime; 6-Bromoindirubin-3'-acetoxime. Grade: 98%. CAS No. 667463-85-6. Molecular formula: C18H12BrN3O3. Mole weight: 398.21.
(E/Z)-BIO-acetoxime, a potent and selective GSK-3α/β inhibitor, with an IC50 of 10 nM, shows more than 200-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B with IC50s of 2.4, 4.3, 63 μM, respectively. Synonyms: GSK-3 Inhibitor X; 2H-Indol-2-one, 3-[3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-; [2-(6-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene)-2H-indol-3-yl]amino acetate. Grade: ≥95%. CAS No. 740841-15-0. Molecular formula: C18H12BrN3O3. Mole weight: 398.21.
4-Phenylbut-3-en-2-one oxime
4-Phenylbut-3-en-2-one oxime. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-PHENYLBUT-3-EN-2-ONE OXIME;BENZYLIDENE ACETOXIME;4-phenylbutenone oxime;4-Phenyl-3-buten-2-one oxime;Methylstyryl ketone oxime. Product Category: Heterocyclic Organic Compound. CAS No. 2887-98-1. Molecular formula: C10H11NO. Mole weight: 161.2. Purity: 0.96. IUPACName: (NE)-N-[(E)-4-phenylbut-3-en-2-ylidene]hydroxylamine. Canonical SMILES: CC(=NO)C=CC1=CC=CC=C1. Density: 0.97g/cm³. ECNumber: 220-752-5. Product ID: ACM2887981. Alfa Chemistry ISO 9001:2015 Certified.
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