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Acetylcorynoline. Group: Biochemicals. Grades: Plant Grade. CAS No. 18797-80-3. Pack Sizes: 10mg. Molecular Formula: C23H23NO6, Molecular Weight: 409.43. US Biological Life Sciences.
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Acetylcorynoline
Acetylcorynoline is the major alkaloid component derived from Corydalis bungeana , and has anti-inflammatory properties [1]. Uses: Scientific research. Group: Natural products. CAS No. 18797-80-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N0759.
Acetylcorynoline
Acetylcorynoline, which can be extracted from the tubers of Corydalis ambigua, inhibits the maturing of bone marrow-derived dendritic cells in mice. However, it is only cytotoxic in amounts of greater than 20 μM. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. Acetylcorynoline significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; prevents α-synuclein aggregation; recovers lipid content in OW13 strain; restores food-sensing behavior, and dopamine levels; and prolongs life-span in 6-hydroxydopamine-treated N2 strain, thus showing its potential as a possible antiparkinsonian drug. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. Uses: Antifungal/anti-inflammatory. Synonyms: (5bR,6S,12bR)-5b,6,7,12b,13,14-Hexahydro-5b,13-dimethyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol 6-acetate; Corynoline acetate; O-Acetylcorynoline; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, 6-acetate, (5bR,6S,12bR)-. Grades: >98%. CAS No. 18797-80-3. Molecular formula: C23H23NO6. Mole weight: 409.43.
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