adenosine 3',5'-cyclic monophosphate sodium salt Suppliers USA
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Adenosine 3',5'-cyclic monophosphate sodium salt. Group: Biochemicals. Alternative Names: cAMP sodium salt. Grades: Highly Purified. CAS No. 37839-81-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C10H11N5NaO6P. US Biological Life Sciences.
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Adenosine 3',5'-cyclic monophosphate sodium salt
Adenosine 3',5'-cyclic monophosphate sodium salt is an indispensable constituent within the realm of biomedical exploration, operating as an ancillary courier engendering intracellular signal transduction. Its pervasive application embraces a multifarious array of cellular proclivities, encompassing metabolic processes, genetic manifestation and neural transmission. Synonyms: cAMP sodium salt; D-Adenosine 3',5'-cyclic monophosphate sodium salt. Grades: 97%. CAS No. 37839-81-9. Molecular formula: C10H11N5NaO6P. Mole weight: 351.19.
8-(4-Chlorophenylthio)adenosine 3?,5?-cyclic monophosphate sodium salt
Adenosine 3',5'-cyclic monophosphate,2'-O-anthraniloyl-,sodium salt
Adenosine 3',5'-cyclic monophosphate,2'-O-anthraniloyl-,sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ANT-CAMP, NA;ANT-CAMP SODIUM SALT;ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, 2'-O-ANTHRANILOYL-, SODIUM SALT;2'-O-ANTHRANILOYLADENOSINE 3':5'-CYCLIC MONOPHOSPHA;2'-O-anthraniloyladenosine 3':5'-cyclic monophosphate;2μ-Anthraniloyl-cAMP;2μ-O-Anthraniloyladenos. Product Category: Heterocyclic Organic Compound. CAS No. 142702-29-2. Molecular formula: C17H16N6NaO7P. Mole weight: 470.31. Product ID: ACM142702292. Alfa Chemistry ISO 9001:2015 Certified.
Adenosine 3,5-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2-O-Methyl-, Sodium Salt (8-CPT-2-O-Me-cAMP, Na)
A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) [also called cAMP-guanine nucleotide-exchange factors (cAMP-GEF)] in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA. Note: 5uMol=2.54mg. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5umol. US Biological Life Sciences.
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Adenosine 3,5-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt (8-CPT-cAMP, Na)
Cell-permeable cAMP analog that activates both protein kinase A and protein kinase G. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Also acts as a potent inhibitor of cGMP-specific phosphodiesterase (IC50=900nM). Inhibits cAMP-specific phosphodiesterase at much higher concentrations (IC50=25uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 93882-12-3. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?PS · Na. US Biological Life Sciences.
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Adenosine 3?,5?-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt - CAS 93882-12-3
Cell-permeable cAMP analog that activates both protein kinase A and protein kinase G. Group: Fluorescence/luminescence spectroscopy.
Adenosine 3,5-cyclic Monophosphate, 8-Bromo-, Sodium Salt (8-Bromo-cAMP, Na)
Cell-permeable cAMP analog that has greater resistance to phosphodiesterases than cAMP. Preferentially activates protein kinase A (PKA). Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Group: Biochemicals. Grades: Highly Purified. CAS No. 76939-46-3. Pack Sizes: 10mg. US Biological Life Sciences.
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Adenosine 3?,5?-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 76939-46-3
Cell-permeable cAMP analog that has greater resistance to phosphodiesterases than cAMP. Group: Fluorescence/luminescence spectroscopy.
Adenosine 3,5-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt (6-Bnz-cAMP, Na)
A potent cell-permeable activator of cAMP-dependent protein kinase (PKA). Activates both type 1 and type 2 PKA and binds to the cAMP binding site 2 on the regulatory subunit of PKA. It is only slowly metabolized by cyclic nucleotide-dependent phosphodiesterases. Due to its considerably increased lipophilicity, it has sufficient membrane permeability for many biological systems. Group: Biochemicals. Grades: Highly Purified. CAS No. 30275-80-0. Pack Sizes: 10umol. US Biological Life Sciences.
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Adenosine 3?,5?-cyclic Monophosphate, N?,O2?-Dibutyryl-, Sodium Salt - CAS 16980-89-5
This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA. Group: Fluorescence/luminescence spectroscopy.
Adenosine-3,5-cyclic Monophosphate Sodium Salt
Adenosine-3,5-cyclic Monophosphate is an Adenosine derivative useful as anticancer agent. Group: Biochemicals. Alternative Names: Adenosine Cyclic 3',5'-(Hydrogen Phosphate) Monosodium Salt; 3',5'-AMP Sodium Salt; Adenosine 3',5'-Phosphoric Acid Sodium Salt; Cyclic 3',5'-AMP Sodium Salt; Cyclic 3',5'-Adenosine Monophosphate Monosodium Salt; Cyclic AMP Sodium; Cyclic AMP Sodium Salt; cAMP Sodium Salt. Grades: Highly Purified. CAS No. 37839-81-9. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Adenosine-3',5'-cyclic Monophosphate Sodium Salt (A-3:5-MP, cAMP, Na)
A key regulator of many cellular reactions. Released in response to hormonal stimulation. An activator of protein kinase A. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 37839-81-9. Pack Sizes: 100mg, 1g. US Biological Life Sciences.
Worldwide
Adenosine-3,5-cyclic Monophosphate Sodium Salt (A-3:5-MP, cAMP, Na)
A key regulator of many cellular reactions. Released in response to hormonal stimulation. An activator of protein kinase A. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 37839-81-9. Pack Sizes: 1g. Molecular Formula: C??H??N?O?P · Na. US Biological Life Sciences.
Worldwide
N6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt
N6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt, a biomedical marvel, takes center stage for addressing a myriad of ailments. Its profound influence on the intricate cellular signaling pathways, most notably the cyclic adenosine monophosphate (cAMP) pathway, cannot be overstated. Possessing the remarkable ability to function as both an agonist and antagonist, this molecular masterpiece orchestrates the modulation of cAMP-dependent processes. Synonyms: sodium N-[9-[(4aR,6R,7aS)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]purin-6-yl]butanamide. Grades: 95%. CAS No. 108347-96-2. Molecular formula: C14H17N5O6P·Na. Mole weight: 405.28.
2',3'-cAMP sodium salt
2',3'-cAMP is a positional isomer of 3',5'-cAMP that is produced by organ systems such as rat and mouse kidney and mouse brain through RNA degradation. When injured, organisms could produce 2',3'-cAMP and release it into the extracellular compartment. Synonyms: Adenosine-2':3'-cyclic monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 37063-35-7. Molecular formula: C10H11N5NaO6P. Mole weight: 351.2.
2',3'-cGAMP sodium salt
2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-&beta. 2',3'-cGAMP is an effective adjuvant that boosts the production of antigen-specific antibodies and T cell responses in mice. Synonyms: Cyclic [G(2',5')pA(3',5')p] sodium; cyclic GMP-AMP sodium; 2',3'-cyclic GMP-AMP sodium; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt. Grades: 95%. CAS No. 2734858-36-5. Molecular formula: C20H22N10Na2O13P2. Mole weight: 718.38.
8-[(6-Amino)hexyl]-amino-cAMP
8-[(6-Amino)hexyl]-amino-cAMP, a cyclic adenosine monophosphate analog, has been found to activate protein kinase A in various studies investigating cAMP-dependent signaling and ion channel regulation. It is also being researched as a possible therapeutic approach for diseases related to ion channel dysfunction, including cystic fibrosis. This compound holds potential for advancing our understanding and treatment of these conditions. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P (free acid). Mole weight: 443.39 (free acid).
8-Bromo-cAMP
8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. It inhibits cell growth, decreases proliferation, increases differentiation and induces apoptosis. Synonyms: (8Br-cAMP); 8-Bromo-adenosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 76939-46-3. Molecular formula: C10H11N5O6PBr (free acid). Mole weight: 408.10 (free acid).
8-[Fluo]-cAMP
8-[Fluo]-cAMP is a fluorescent cAMP analogue (λexc494 nm, λem517 nm). Synonyms: 8- (2-[Fluoresceinyl]aminoethylthio) adenosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 293296-57-8. Molecular formula: C33H27N7NaO11PS2. Mole weight: 815.7.
8-NBD-cAMP
8-NBD-cAMP is a fluorescent activator (λexc471 nm, λem536 nm) of cAMP-dependent protein kinase. 8-NBD-cAMP fluoresces strongly in hydrophobic environments. Synonyms: 8- (2-[7-Nitro-4-benzofurazanyl]aminoethylthio) adenosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 221905-51-7. Molecular formula: C18H17N9NaO9PS. Mole weight: 589.41.
Camp sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MolPort-001-030-848, Adenosine-3 ,5 -Monophosphoric Acid, adenosine-3,5-cyclic-monophosphate, X-063151, 37839-81-9. Product Category: Heterocyclic Organic Compound. Appearance: white powder. CAS No. 37839-81-9. Molecular formula: C10H11N5NaO6P. Mole weight: 351.19. Purity: >98.0%(LC). IUPACName: sodium 8-(6-aminopurin-9-yl)-3-oxido-3-oxo-2,4,7-trioxa-3$l^{5}-phosphabicyclo[4.3.0]nonan-9-ol. Canonical SMILES: C1C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)OP(=O)(O1)[O-].[Na+]. Product ID: ACM37839819. Alfa Chemistry ISO 9001:2015 Certified. Categories: Cyclic AMP sodium.
Dibutyryladenosine cyclic 3',5'-monophosphate
Bucladesine is a 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP. It has a role as an agonist, a vasodilator agent and a cardiotonic drug. It is a butyrate ester, a 3',5'-cyclic purine nucleotide and a member of butanamides. It derives from a 3',5'-cyclic AMP. Synonyms: Bucladesine; Dibutyryl 3',5'-cyclic AMP; Bt2 cyclic AMP; 3',5'-Cyclic AMP dibutyrate; n-6,o-2'-dibutyryl adenosine cyclic 3':5'-monophosphate; Cyclic AMP dibutyrate; N6,2'-O-dibutyryl-cAMP; [(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d]; Bucladesine, Disodium Salt; Bucladesine, Monosodium Salt; Bucladesine, Sodium Salt. Grades: 99%. CAS No. 362-74-3. Molecular formula: C18H24N5O8P. Mole weight: 469.39.
Guanosine-3',5'-cyclic monophosphorothioate,rp-isomer sodium salt
Guanosine-3',5'-cyclic monophosphorothioate,rp-isomer sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-PIP-cAMP, 31357-06-9, P0872_SIGMA, CTK8F7436, AG-F-04393, 8-Piperidinoadenosine 3,5-monophosphate sodium salt, 8-Piperidinoadenosine 3 inverted exclamation marka,5 inverted exclamation marka-monophosphate sodium salt, Adenosine,8-piperidino-, cyclic 3,5-(hydrogen phosphate) (8CI);4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.; 8-Piperidino-cyclicAMP; 8-Piperidinoadenosine 3,5-monophosphate; Cyclic 8-piperidino-3,5-AMP. Product Category: Heterocyclic Organic Compound. Appearance: white solid. CAS No. 31357-06-9. Molecular formula: C15H20N6O6P.Na. Mole weight: 434.32. Purity: 0.96. IUPACName: sodium;(4aR,6R,7R,7aS)-6-(6-amino-8-piperidin-1-ylpurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol. Canonical SMILES: C1CCN(CC1)C2=NC3=C(N2C4C(C5C(O4)COP(=O)(O5)[O-])O)N=CN=C3N.[Na+]. Product ID: ACM31357069. Alfa Chemistry ISO 9001:2015 Certified.
Mant-cAMP
Mant-cAMP is a biochemical compound commonly used in biomedicine for research purposes. It is a stable analog of cyclic adenosine monophosphate (cAMP). Researchers utilize Mant-cAMP to study cellular signaling pathways, particularly those involving cAMP-dependent processes. Its applications range from investigating drug targets and receptor interactions to examining the effects of cAMP on various diseases, such as cancer and cardiovascular disorders. Synonyms: 2'-O-(N-Methyl-anthraniloyl)-adenosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 98 % by HPLC. CAS No. 83707-14-6. Molecular formula: C18H19N6O7P (free acid). Mole weight: 462.35 (free acid).
1-NO-cAMP
1-NO-cAMP is a polar cAMP analogue used for receptor mapping studies. Synonyms: Adenosine- 1- N- oxide- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 75912-25-3. Molecular formula: C10H11N5O7P · Na. Mole weight: 367.2.
2-Cl-cIMP
2-Cl-cIMP is an exceptionally powerful cyclic adenosine monophosphate (cAMP) analog that possesses the ability to effortlessly traverse cell membranes. It has become a widespread staple within the realm of biomedical research, notably enabling the extensive examination of the crucial cAMP signaling pathway's involvement in an array of complex ailments. The versatile nature of 2-Cl-cIMP renders it an invaluable asset in the study of intricate cellular signaling mechanisms and the pioneering development of groundbreaking therapeutic approaches. Synonyms: 2- Chloroinosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 52301-30-1. Molecular formula: C10H9ClN4O7P · Na. Mole weight: 386.6.
8-Bromoadenosine 3',5'-Cyclic Monophosphothioate Sp-Isomer Sodium Salt
8-CPT-cAMP is an activator of cAMP- and cGMP-dependent protein kinase and of Epac. It has an improved membrane permeability, phosphodiesterase stability and selectivity for site B of cAK type II. Uses: Enzyme inhibitors. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 93882-12-3. Molecular formula: C16H14ClN5O6PS · Na. Mole weight: 493.8.
8-[Fluo]-cAMP
8-[Fluo]-cAMP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8- (2- [Fluoresceinyl]aminoethylthio)adenosine- 3', 5'- cyclic monophosphate sodium salt. Appearance: White powder. CAS No. 293296-57-8. Molecular formula: C33H2NO11PS2·Na. Mole weight: 815.7. Purity: 0.95. Product ID: ACM293296578. Alfa Chemistry ISO 9001:2015 Certified.
8-Piperidinoadenosine-3',5'-cyclic monophosphorothioate,sp-isomer sodium salt
8-Piperidinoadenosine-3',5'-cyclic monophosphorothioate,sp-isomer sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-piperidinoadenosine-3',5'-cyclicmonophosphorothioate,sp-isomer,(sp-8-pip-camps),sodiumsalt;ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-PIPERIDINO-, SP-ISOMER, SODIUM SALT;8-PIPERIDINOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT. Product Category: Heterocyclic Organic Compound. CAS No. 156816-35-2. Molecular formula: C15H20N6NaO5PS. Mole weight: 450.39. Product ID: ACM156816352. Alfa Chemistry ISO 9001:2015 Certified. Categories: rp-8-pip-camps.
Adenosine 3?,5?-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt
A potent, cell-permeable, and reversible metabolically-stable cAMP antagonist that inhibits cAMP-dependent protein kinase and shows preference for PKA type I. Group: Fluorescence/luminescence spectroscopy.
Adenosine 3?,5?-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt
A potent cell-permeable, metabolically-stable activator of cAMP-dependent protein kinase (PKA). Group: Fluorescence/luminescence spectroscopy.
Adenosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt (Sp-8-Br-cAMPS, Na)
A potent cell-permeable, metabolically-stable activator of cAMP-dependent protein kinase (PKA). Induces guanine nucleotide exchange factor activity of GEFI (also known as Epac) and GEFII towards Rap1 both in vivo and in vitro. Significantly more lipophilic and cell-permeable than Sp-cAMPS. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5umol. US Biological Life Sciences.
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Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt
Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 73208-40-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C10H11N5O5PS·Na. US Biological Life Sciences.
Worldwide
Adenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt
Adenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt. Group: Biochemicals. Alternative Names: (S)-Adenosine 3',5'-cyclic hydrogen phosphorothioate triethylammonium salt; Sp-cAMPS. Grades: Highly Purified. CAS No. 71774-13-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C10H11N5O5PS·Na. US Biological Life Sciences.
Adenosine,8-chloro-,cyclic 3',5'-[hydrogen(S)-phosphorothioate](9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT;ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-CHLORO-, SP-ISOMER, SODIUM SALT;SP-8-CL-CAMPS, NA;SP-8-CL-CAMPS SODIUM SALT;8-chloroadenosine-3',5'-cyclicmonophosphorothioate;8-chl. Product Category: Heterocyclic Organic Compound. CAS No. 142754-28-7. Molecular formula: C10H11ClN5O5PS. Mole weight: 401.7. Purity: 0.96. IUPACName: cyclohexane-1,2-diamine; platinum(2+); 3,4,5-trihydroxy-1-oxidocyclohexane-1-carboxylate. Density: g/cm³. Product ID: ACM142754287. Alfa Chemistry ISO 9001:2015 Certified.
c[3'-AHC-G(2',5')pA(3',5')p]
c[3'-AHC-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. Synonyms: Cyclic (3'- O- (6- aminohexylcarbamoyl)guanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C27H38N12O14P2 (free acid). Mole weight: 816.6 (free acid).
c[3'-Fluo-AHC-G(2',5')pA(3',5')p]
c[3'-Fluo-AHC-G(2',5')pA(3',5')p] is a fluorescent analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator. Synonyms: Cyclic (3'-O- (6-[fluoresceinyl]aminohexylcarbamoyl) guanosine- (2'?5') -monophosphate-adenosine- (3'?5') -monophosphate) , sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C48H48N12O20P2. Mole weight: 1174.9.
c[8-AET-G(2',5')pA(3',5')p]
c[8-AET-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which is used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. c[G(2',5')pA(3',5')p] is the metazoan second messenger produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. Synonyms: Cyclic (8- (2- aminoethylthio)guanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C22H29N11O13P2S (free acid). Mole weight: 749.6 (free acid).
c[8-Br-G(2',5')pA(3',5')p]
c[8-Br-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger, which can be used for binding studies and as precursor for further modifications with spacers or labels. c[G(2',5')pA(3',5')p] is the metazoan second messenger produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. Synonyms: Cyclic (8- bromoguanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H23BrN10O13P2 (free acid). Mole weight: 753.3 (free acid).
c[8-Fluo-AET-G(2',5')pA(3',5')p]
c[8-Fluo-AET-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Synonyms: Cyclic(8-(2-[fluoresceinyl]aminoethylthio)-guanosine-(2'?5')-monophosphate-adenosine-(3'?5')-monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C43H39N11O19P2S (free acid). Mole weight: 1107.9 (free acid).
c[G(2',5')p-2'-AHC-A(3',5')p]
c[G(2',5')p-2'-AHC-A(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. Synonyms: Cyclic (guanosine- (2' -≥ 5')- monophosphate- 2'- O- (6- aminohexylcarbamoyl)adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C27H38N12O14P2 (free acid). Mole weight: 816.6 (free acid).
c[G(2',5')p-2'-Fluo-AHC-A(3',5')p]
c[G(2',5')p-2'-Fluo-AHC-A(3',5')p] is a fluorescent analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator. Synonyms: Cyclic (guanosine- (2'?5') -monophosphate-2'-O- (6-[fluoresceinyl]aminohexylcarbamoyl) adenosine- (3'?5') -monophosphate) , sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C48H48N12O20P2. Mole weight: 1174.9.
Rp-8-CPT-cAMPS
Rp-8-CPT-cAMPS is an analog of Rp-cAMPS and a competitive inhibitor of protein kinase A type I and II (cAMP antagonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-8-Br-cAMPS, it is more lipophilic and membrane-permeant. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129735-01-9. Molecular formula: C16H14ClN5O5PS2 · Na. Mole weight: 509.8.
Rp-cAMPS, sodium salt
Rp-cAMPS is a competitive inhibitor of protein kinase A type I and II (cAMP antagonist), which has a higher affinity for type II of protein kinase A. It exhibits a resistant effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Uses: Protein kinase inhibitors. Synonyms: Adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 73208-40-9. Molecular formula: C10H11N5O5PS · Na. Mole weight: 367.3.
Sp-8-CPT-cAMPS
Sp-8-CPT-cAMPS is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129693-13-6. Molecular formula: C16H14ClN5O5PS2 · Na. Mole weight: 509.8.
Sp-cAMPS, sodium salt
Sp-cAMPS is an activator of protein kinase A (cAMP agonist). It exhibits high resistance against cyclic nucleotide phosphodiesterases and membrane permeability in organisms. Uses: Protein kinase inhibitors. Synonyms: Adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 71774-13-5. Molecular formula: C10H11N5O5PS · Na. Mole weight: 367.3.
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