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| Product | Description | |
|---|---|---|
| AG-1478 | AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. Uses: Enzyme inhibitors. Synonyms: Tyrphostin AG-1478; AG-1478; AG1478; AG 1478. Grades: >98%. CAS No. 153436-53-4. Molecular formula: C16H14ClN3O2. Mole weight: 315.75. |  |
| AG-1478 | AG-1478 (Tyrphostin AG-1478) is a selective EGFR tyrosine kinase inhibitor with IC 50 of 3 nM. AG-1478 has antiviral effects against HCV and encephalomyocarditis virus (EMCV). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrphostin AG-1478; NSC 693255. CAS No. 153436-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13524. |  |
| AG 1478 hydrochloride | The hydrochloride salt form of AG 1478, which has been found to be an epidermal growth factor receptor tyrosine kinase inhibitor. Synonyms: AG 1478 hydrochloride; AG1478 hydrochloride; AG-1478 hydrochloride; N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine hydrochloride. Grades: ≥98% by HPLC. CAS No. 170449-18-0. Molecular formula: C16H14ClN3O2.HCl. Mole weight: 352.22. | |
| Lysophosphatidylethanolamines, egg | Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine. CAS No. 97281-40-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-156041. | |
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