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| Product | Description | |
|---|---|---|
| Ajmaline | Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC 50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cardiorythmine; (+)-Ajmaline. CAS No. 4360-12-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1167. |  |
| Ajmaline | Ajmaline is an alkaloid which could be extracted from Rauwolfia serpentina. It is an antiarrhythmic agent, acting through changing the shreshold and the shape of cardiac action potentials. Synonyms: Cardiorythmine; Ajmalin; Gilurytmal; Raugalline. Grades: >95%. CAS No. 4360-12-7. Molecular formula: C20H26N2O2. Mole weight: 326.43. |  |
| Ajmaline | An antiarrhythmic agent isolated from Rauwolfia serpentina. Group: Biochemicals. Alternative Names: (17R,21α-Ajmalan-17,21-diol; (+)-Ajmaline; Cardiorythmine; Gilurytmal; Ignazin; Merabitol; NSC 15627; Raugalline; Rauwolfin; Rauwolfine; Rhytmaton; Ritmos; Rytmalin; Siddiqui; Tachmalin; Takycor. Grades: Highly Purified. CAS No. 4360-12-7. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| acetylajmaline esterase | This plant enzyme is responsible for the last stages in the biosynthesis of the indole alkaloid ajmaline. The enzyme is highly specific for the substrates 17-O-acetylajmaline and 17-O-acetylnorajmaline as the structurally related acetylated alkaloids vinorine, vomilenine, 1,2-dihydrovomilenine and 1,2-dihydroraucaffricine cannot act as substrates. This is a novel member of the GDSL family of serine esterases/lipases. Group: Enzymes. Synonyms: AAE;2β(R)-17-O-acetylajmalan:acetylesterase; acetylajmalan esterase. Enzyme Commission Number: EC 3.1.1.80. CAS No. 110183-46-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3509; acetylajmaline esterase; EC 3.1.1.80; 110183-46-5; AAE;2β(R)-17-O-acetylajmalan:acetylesterase; acetylajmalan esterase. Cat No: EXWM-3509. |  |
| 1,2-dihydrovomilenine reductase | Forms part of the ajmaline biosynthesis pathway. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.73. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1342; 1,2-dihydrovomilenine reductase; EC 1.3.1.73. Cat No: EXWM-1342. | |
| perakine reductase | The biosynthesis of raucaffrinoline from perakine is a side route of the ajmaline biosynthesis pathway. The enzyme is a member of the aldo-keto reductase enzyme superfamily from higher plants. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.317. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0229; perakine reductase; EC 1.1.1.317. Cat No: EXWM-0229. | |
| Secologanin | Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 19351-63-4. Pack Sizes: 1 mg. Product ID: HY-125598. | |
| vinorine hydroxylase | A heme-thiolate protein (P-450). Forms a stage in the biosynthesis of the indole alkaloid ajmaline. Group: Enzymes. Enzyme Commission Number: EC 1.14.13.75. CAS No. 162875-03-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0882; vinorine hydroxylase; EC 1.14.13.75; 162875-03-8. Cat No: EXWM-0882. | |
| vinorine synthase | The reaction proceeds in two stages. The indole nitrogen of 16-epivellosimine interacts with its aldehyde group giving an hydroxy-substituted new ring. This alcohol is then acetylated. Also acts on gardneral (11-methoxy-16-epivellosimine). Generates the ajmalan skeleton, which forms part of the route to ajmaline. Group: Enzymes. Enzyme Commission Number: EC 2.3.1.160. CAS No. 88844-97-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2100; vinorine synthase; EC 2.3.1.160; 88844-97-7. Cat No: EXWM-2100. | |
| vomilenine reductase | Forms part of the ajmaline biosynthesis pathway. Group: Enzymes. Enzyme Commission Number: EC 1.5.1.32. CAS No. 462127-03-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1514; vomilenine reductase; EC 1.5.1.32; 462127-03-3. Cat No: EXWM-1514. | |
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