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| Product | Description | |
|---|---|---|
| Aliskiren hemifumarate | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Aliskiren hemifumarate | Aliskiren (CGP 60536; CGP60536B; SPP 100) hemifumarate is an orally active and selective renin inhibitor, with IC 50 of 1.5 nM. Aliskiren hemifumarate can be used for the research of hypertension, cardiovascular diseases and cancer cachexia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 60536 hemifumarate; CGP60536B hemifumarate; SPP 100 hemifumarate. CAS No. 173334-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12177. |  |
| Aliskiren hemifumarate | Aliskiren is a direct renin inhibitor used for the treatment of essential hypertension. Synonyms: (αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeno-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonaoyl-2-methyl-propyl)-amide hemifumarate. Grades: 99%. CAS No. 173334-58-2. Molecular formula: C30H53N3O6·1/2C4H4O4. Mole weight: 1219.6. |  |
| Aliskiren Hemifumarate | An orally active, synthetic nonpeptide renin inhibitor. Antihypertensive. Group: Biochemicals. Alternative Names: (α S, γ S, δ S, zS) -δ -Amino-N- (3-amino-2, 2-dimethyl-3-oxopropyl) -γ -hydroxy-4-methoxy-3- (3-methoxypropoxy) -α , z-bis (1-methylethyl) benzeneoctanamide Hemifumarate; CGP 60536; CGP60536B; Rasilez Hemifumarate; SPP 100; Tekturna Hemifumarate. Grades: Highly Purified. CAS No. 173334-58-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. US Biological Life Sciences. |  Worldwide |
| Aliskiren Hemifumarate (SSSRisomer) Impurity | An impurity of Aliskiren. Synonyms: (αS,γS,δS,ζR)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)benzeneoctanamide (2E)-2-Butenedioate (2:1). Grades: > 95%. CAS No. 1630036-82-6. Molecular formula: C30H53N3O6.1/2(C4H4O4). Mole weight: 609.79. | |
| Renin Inhibitor (Aliskiren Hemifumarate) | A non-peptide, direct renin inhibitor (IC50 = 0.6nM for human renin) and an anti-hypertensive agent. Aliskiren confers neuronal resistance to A beta toxicity in primary rat cortical cultures. Group: Biochemicals. Alternative Names: (2S,4S,5S,7S)-N-(2-Carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide Hemifumarate. Grades: Highly Purified. CAS No. 173334-58-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (2R,4R,5R,7S)-Aliskiren Fumarate (2:1) | (2R,4R,5R,7S)-Aliskiren Fumarate (2:1) is an isomer of Aliskiren Hemifumarate (A536001), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C64H110N6O16, Molecular Weight: 1219.58999999999. US Biological Life Sciences. | Worldwide |
| (2S,4S,5S,7R)-Aliskiren Fumarate (2:1) | (2S,4S,5S,7R)-Aliskiren Fumarate (2:1) is an isomer of Aliskiren Hemifumarate (A536001), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. CAS No. 1630036-82-6. Pack Sizes: 500ug, 5mg. Molecular Formula: C64H110N6O16, Molecular Weight: 1219.58999999999. US Biological Life Sciences. | Worldwide |
| Aliskiren | Aliskiren hemifumarate appears to bind to both the hydrophobic S1/S3-binding pocket and to a large, distinct subpocket that extends from the S3-binding site towards the hydrophobic core of renin. Oral bioavailability of Aliskiren hemifumarate is 2.4% in rats, 16% in marmosets and about 2.5% in humans. Aliskiren hemifumarate (< 10 mg/kg, oral) inhibits plasma renin activity and lowers blood pressure in sodium-depleted marmosets.Once-daily oral treatment with Aliskiren hemifumarate lowers blood pressure effectively, with a safety and tolerability profile, in patients with mild-to-moderate hypertension. Uses: Antihypertensive agent; renin; antagonists and inhibitors. Synonyms: CGP 60536; CGP60536B; Rasilez; SPP 100; Tekturna. Grades:>98%. CAS No. 173334-57-1. Molecular formula: C30H53N3O6. Mole weight: 551.76. | |
| R-(+)-4-Benzyl-2-oxazolidinone | intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan. CAS No. 102029-44-7. Product ID: 1-01314. Molecular formula: C10H11NO2. Mole weight: 177.2. Purity: 99% ee 99.5%. Properties: mp 88-90°C[a]18 +64° (c=1 CHCl3). Source : |  |
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