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| Product | Description | |
|---|---|---|
| Allopurinol sodium | Allopurinol sodium is a potent and orally active xanthine oxidase inhibitor with an IC 50 value of 0.2-50 μM. Allopurinol sodium can be used in the research of hyperuricemia and gout. Allopurinol sodium decreases the expression of HIF-1α and HIF-2α protein. Allopurinol sodium shows anti-depressant and anti-nociception activity. Anti-leishmanial effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 17795-21-0. Pack Sizes: 10 mg; 25 mg. Product ID: HY-B0219A. |  |
| Allopurinol Sodium | Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM. Synonyms: Sodium allopurinol; Allopurinol sodium salt; NSC 108836; 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one,monosodiumsalt. Grades: >98%. CAS No. 17795-21-0. Molecular formula: C5H3N4NaO. Mole weight: 158.09. |  |
| Native Microbial Xanthine Oxidase | Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species. Xanthine oxidase was shown to be involved in the reduction of cytochrome c by the generation of superoxide anions following the oxidation of xanthine. These free radicals are responsible for reducing cytochrome c. Allopurinol is a synthetic drug show to inhibit xanthine oxidase. Applications: This enzyme is useful for enzymatic determination of inorganic phosphorus, 5?-nucleotidase and adenosine deaminase when coupled with purine-nucleoside phosphorylase and uricase. Group: Enzymes. Synonyms: Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17. Enzyme Commission Number: EC 1.17.3.2. CAS No. 9002-17-9. XAO. Mole weight: mol wt ~160 kDa. Activity: > 7 units/mg solid. Storage: -20°C. Form: Lyophilized powder containing BSA and sodium glutamate as stabilizers. Source: Microbial. Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17.3.2; 9002-17-9; XOD; Xanthine:oxygen oxidoreductase; hypoxanthine oxidase; hypoxanthine:oxygen oxidoreductase; Schardinger enzyme; hypoxanthine-xanthine oxidase; xanthine:O2 oxidoreductase; xanthine:xanthine oxidase. Cat No: NATE-0733. |  |
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