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| Product | Description | |
|---|---|---|
| Aloxistatin | Aloxistatin is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain, which predicted to function against SARS-CoV-2 infection. Synonyms: L-trans-Epoxysuccinyl(OEt)-Leu-3-methylbutylamide; L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester; (2S, 3S) -3-[[[ (1S) -3-Methyl-1-[[ (3-methylbutyl) amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic Acid Ethyl Ester; E 64c ethyl ester; E 64d; EP 453; EST; Loxistatin; NSC 694281; (2S,3S)-trans-Epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester. Grades: 98%. CAS No. 88321-09-9. Molecular formula: C17H30N2O5. Mole weight: 342.43. |  |
| Aloxistatin (E-64d) | Aloxistatin (E-64d), is a selective cysteine protease inhibitor or calpain and autophagy inhibitor. E-64d prevents in vitro cerulein- induced trypsinogen activation. E-64d can enter the intact cell and inhibit calpain. E-64d has been shown safe for the treatment of Alzheimer's disease in human. E-64d is potentially useful in the treatment of developmental seizure-induced brain damage both by regulating abnormal zinc signal transduction and through the modulation of altered lipid metabolism via ApoE/clusterin pathway in hippocampus. Uses: Designed for use in research and industrial production. Additional or Alternative Names: E-64d; E 64d; E64d; E64-d; E64-d; E64 d; ethyl ester Loxistatin; NSC 694281; NSC694281; NSC-694281; EST; EP-453; EP453; EP 453; Aloxistatin. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 88321-09-9. Molecular formula: C17H30N2O5. Mole weight: 342.44. Purity: >98%. IUPACName: ethyl (2S,3S)-3-(((S)-1-(isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylate. Canonical SMILES: CCOC([C@@H]1[C@@H](C(N[C@H](C(NCCC(C)C)=O)CC(C)C)=O)O1)=O. Product ID: ACM88321099. Alfa Chemistry ISO 9001:2015 Certified. |  |
| E-64d | E-64d is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. E-64d has been used in combination with Prepstatin A to interfere with autolysosomal digestion. E-64d displays neurovascular and neuronal protective effects after focal cerebral ischemia in rats. Group: Biochemicals. Alternative Names: (2S, 3S) -3- [ [ [ (1S) -3-Methyl-1- [ [ (3-methylbutyl) amino] carbonyl] butyl] amino] carbonyl] -2-oxiranecarboxylic Acid Ethyl Ester; Aloxistatin; E 64c ethyl ester; E 64d; EP 453; EST; EST (pharmaceutical); Loxistatin; NSC 694281. Grades: Highly Purified. CAS No. 88321-09-9. Pack Sizes: 2.5mg. US Biological Life Sciences. |  Worldwide |
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