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| Product | Description | |
|---|---|---|
| Alvespimycin | Alvespimycin (17-DMAG) is a potent inhibitor of Hsp90 , binding to Hsp90 with an EC 50 of 62 ± 29 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17-DMAG; KOS-1022; NSC 707545. CAS No. 467214-20-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10389. |  |
| Alvespimycin hydrochloride | Alvespimycin hydrochloride (17-DMAG hydrochloride; KOS-1022; BMS 826476) is a potent inhibitor of Hsp90 , binding to Hsp90 with EC 50 of 62±29 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17-DMAG hydrochloride; KOS-1022 hydrochloride; BMS 826476. CAS No. 467214-21-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 200 mg. Product ID: HY-12024. | |
| 17-DMAG Hydrochloride (17- (Di methyl aminoethylamino) -17-demethoxygeldanamycin Hydrochloride) (17-DMAG Hydrochloride, NSC-707545, Alvespimycin) | 17-DMAG Hydrochloride (17- (Di methyl aminoethylamino) -17-demethoxygeldanamycin Hydrochloride) (17-DMAG Hydrochloride, NSC-707545, Alvespimycin). Group: Biochemicals. Grades: Highly Purified. CAS No. 150270-08-9. Pack Sizes: 250mg. Molecular Formula: C32H48N4O8 HCl, Molecular Weight: 653.21. US Biological Life Sciences. |  Worldwide |
| 17-DMAG hydrochloride | 17-DMAG hydrochloride (Alvespimycin hydrochloride) is the hydrochloride salt of alvespimycin, an analogue of the antineoplastic benzoquinone antibiotic geldanamycin. Alvespimycin binds to Hsp90, a chaperone protein that aids in the assembly, maturation and folding of proteins. Subsequently, the function of Hsp90 is inhibited, leading to the degradation and depletion of its client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction. Synonyms: 17-DMAG HCl; Alvespimycin HCl; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin Hydrochloride; 17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride; 17-Demethoxy-17-[[2- (dimethylamino) ethyl]amino]geldanamycin Hydrochloride; 17-[2-(Dimethylamino)ethylamino]-17-desmethylgeldanamycin Hydrochloride; Alvespimycin Hydrochloride; DMAG Hydrochloride; NSC 707545 Hydrochloride; 17-DMAG Hydrochloride. Grades: >98%. CAS No. 467214-21-7. Molecular formula: C32H48N4O8.HCl. Mole weight: 653.21. |  |
| 17-N- (2-Di methyl aminoethylamino) -17-demethoxy Geldanamycin Hydrochloride | 17-DMAG is an analogue of Gelamycin and 17- (Allylamino) geldanamycin. 17-DMAG acts as a Hsp90 inhibitor and displays more potent antitumor activity than 17-AAG. Group: Biochemicals. Alternative Names: 17-Demethoxy-17- [ [2- (dimethylamino) ethyl] amino] geldanamycin Hydrochloride; 17-N- (2-Di methyl aminoethylamino) -17-demethoxygeldanamycin Hydrochloride; 17-[2- (Dimethylamino) ethylamino]-17-desmethylgeldanamycin Hydrochloride; Alvespimycin Hydrochloride; DMAG Hydrochloride; NSC 707545 Hydrochloride; 17-DMAG Hydrochloride. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
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