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Ambuic acid Ambuic acid exhibits antimicrobial activity against Staphylococcus aureus , with IC 50 of 43.9 μM for strain ATCC 6538. Ambuic acid is an inhbitor for the biosynthesis of cyclic peptide quorum sensing molecules (quormones) in gram-positive bacteria. Ambuic acid exhibits anti-inflammatory activity through ERK/JNK/MAPK signaling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Ambuic acid. CAS No. 340774-69-8. Pack Sizes: 500 μg. Product ID: HY-126858. MedChemExpress MCE
Ambuic acid Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species. Antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP). Synonyms: (+)-Ambuic acid; (2E,5R,6R,7R,8E,10E)-2-Methyl-5,9-carbonyl-5,6-epoxy-7-hydroxy-8-(hydroxymethyl)-2,8,10-hexadecatrienoic acid. Grades: ≥95%. CAS No. 340774-69-8. Molecular formula: C19H26O6. Mole weight: 350.41. BOC Sciences
Ambuic acid Antibiotic. Antibacterial. Antifungal. Inhibits the biosynthesis of cyclic peptide quormones in Gram-positive bacteria. Lead compound for antipathogenic drugs that target the quorum-sensing-mediated virulence expression of Gram-positive bacteria. Group: Biochemicals. Alternative Names: (+)-Ambuic acid. Grades: Highly Purified. CAS No. 340774-69-8. Pack Sizes: 250ug, 1mg. Molecular Formula: C19H26O6. US Biological Life Sciences. USBiological 3
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