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| Product | Description | |
|---|---|---|
| Ametantrone | Ametantrone (AM) is a topoisomerase II inhibitor leading to covalent cross-links in DNA of tumor cells. It is a synthetic 9,10-anthracenedione containing two (hydroxyethylamino)ethylamino residues at positions 1 and 4. Along with other anthraquinones and anthracyclines, it shares a polycyclic intercalating moiety and charged side chains that stabilize DNA binding. Synonyms: CI881; CI 881; CI-881; NSC196473; NSC 287513; NSC-196473; NSC 287513; 1, 4-bis[2- (2-hydroxyethylamino) ethylamino]anthracene-9, 10-dione. CAS No. 64862-96-0. Molecular formula: C22H28N4O4. Mole weight: 412.49. |  |
| Ametantrone Acetate | Ametantrone is a topoisomerase II inhibitor of the anthrapyrazole family. It can cause covalent cross-links in DNA, so it can be used as a antineoplastic agent. Uses: Antineoplastic agent. Synonyms: CI-881; CI 881; CI881; NSC 287513; NSC-287513; NSC287513; 1, 4-bis ( (2- ( (2-hydroxyethyl) amino) ethyl) amino) anthracene-9, 10-dione diacetate. Grades: 98%. CAS No. 70711-40-9. Molecular formula: C26H36N4O8. Mole weight: 532.59. | |
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