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| Product | Description | |
|---|---|---|
| Amifostine | Amifostine is a phosphorylated aminosulfhydryl compound. After dephosphorylation of amifostine by alkaline phosphatase to an active free sulfhydryl (thiol) metabolite, the thiol metabolite binds to and detoxifies cytotoxic platinum-containing metabolites of cisplatin and scavenges free radicals induced by cisplatin and ionizing radiation. The elevated activity of this agent in normal tissues results from both the relative abundance of alkaline phosphatase in normal tissues and the greater vascularity of normal tissues compared to tumor tissues. Uses: Radiation-protective agents. Synonyms: Ethyol; WR2721; WR 2721; WR-2721. Grades: >98%. CAS No. 20537-88-6. Molecular formula: C5H15N2O3PS. Mole weight: 214.22. |  |
| Amifostine | Amifostine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: S-(2-((3-aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate. CAS No. 20537-88-6. Molecular Formula: C5H15N2O3PS. Mole Weight: 214.22. Catalog: APB20537886. |  |
| Amifostine | Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine protects cells from damage by scavenging oxygen-derived free radicals. Amifostine reduces renal toxicity and has antiangiogenic action [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR2721. CAS No. 20537-88-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0639. |  |
| Amifostine | It is a thiophosphate derivative of cysteamine; provides normal cells with selective protection against the toxic effects of cancer chemotherapy and radiation treatment. Group: Biochemicals. Alternative Names: 2-[(3-Aminopropyl)-amino]ethanethiol Dihydrogen Phosphate; Phosphorothioic Acid S-[2-[ (3-Aminopropyl) amino]ethyl]ester; Ethiofos; Gammaphos; SAPEP; CSC-296961; Ethyol. Grades: Highly Purified. CAS No. 20537-88-6. Pack Sizes: 10mg, 100mg. US Biological Life Sciences. |  Worldwide |
| Amifostine hydrate | Amifostine hydrate is a radiation-protective agent. Synonyms: Amifostinum; Amifostine monohydrate; Amifostinum; Amifostina. CAS No. 63717-27-1. Molecular formula: C5H15N2O3PS.H2O. Mole weight: 232.235. | |
| Amifostine Impurity 1 | Amifostine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: S-(2-((3-aminopropyl)amino)ethyl) O-methyl O-hydrogen phosphorothioate. Molecular Formula: C6H17N2O3PS. Mole Weight: 228.25. Catalog: APB03297. | |
| Amifostine Impurity 10 | Amifostine Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(bis(3-aminopropyl)amino)ethanol. CAS No. 17002-55-0. Molecular Formula: C8H21N3O. Mole Weight: 175.27. Catalog: APB17002550. | |
| Amifostine Impurity 11 | Amifostine Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((3-aminopropyl)amino)ethanethiol dihydrochloride. CAS No. 14653-77-1. Molecular Formula: C5H14N2S·2HCl. Mole Weight: 207.2. Catalog: APB14653771. | |
| Amifostine Impurity 12 | Amifostine Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-((3-aminopropyl)azanediyl)diethanol. CAS No. 4985-85-7. Molecular Formula: C7H18N2O2. Mole Weight: 162.23. Catalog: APB4985857. | |
| Amifostine Impurity 13 | Amifostine Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N1,N1-bis(2-bromoethyl)propane-1,3-diamine dihydrobromide. Molecular Formula: C7H16Br2N2·2HBr. Mole Weight: 449.84. Catalog: APB03289. | |
| Amifostine Impurity 14 | Amifostine Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-(propane-1,3-diylbis(azanediyl))diethanol. CAS No. 10563-27-6. Molecular Formula: C7H18N2O2. Mole Weight: 162.23. Catalog: APB10563276. | |
| Amifostine Impurity 15 | Amifostine Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N1,N3-bis(2-bromoethyl)propane-1,3-diamine dihydrobromide. CAS No. 10297-31-1. Molecular Formula: C7H16Br2N2·2HBr. Mole Weight: 449.85. Catalog: APB10297311. | |
| Amifostine Impurity 16 | Amifostine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N1,N1'-(disulfanediylbis(ethane-2,1-diyl))bis(propane-1,3-diamine) tetrahydrochloride. CAS No. 10027-65-3. Molecular Formula: C10H26N4S2·4HCl. Mole Weight: 412.314. Catalog: APB10027653. | |
| Amifostine Impurity 17 | Amifostine Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((3-aminopropyl)amino)ethanol. Molecular Formula: C5H14N2O. Mole Weight: 118.18. Catalog: APB01321. | |
| Amifostine Impurity 18 (Trihydrobromide) | Amifostine Impurity 18 (Trihydrobromide). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-((azanediylbis(propane-3,1-diyl))bis(azanediyl))diethanol trihydrobromide. Molecular Formula: C10H25N3O2·3HBr. Mole Weight: 462.05. Catalog: APB03288. | |
| Amifostine Impurity 2 | Amifostine Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: S-(2-((3-aminopropyl)amino)ethyl) O-ethyl O-hydrogen phosphorothioate. Molecular Formula: C7H19N2O3PS. Mole Weight: 242.28. Catalog: APB03296. | |
| Amifostine Impurity 3 | Amifostine Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: O-(2-((3-aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate. Molecular Formula: C5H15N2O3PS. Mole Weight: 214.22. Catalog: APB03295. | |
| Amifostine Impurity 4 | Amifostine Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((3-aminopropyl)amino)ethyl dihydrogen phosphate. Molecular Formula: C5H15N2O4P. Mole Weight: 198.16. Catalog: APB03294. | |
| Amifostine Impurity 5 | Amifostine Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: S-(2-((3-aminopropyl)(hydroxy)amino)ethyl) O,O-dihydrogen phosphorothioate hydrochloride. Molecular Formula: C5H15N2O4PS·HCl. Mole Weight: 266.68. Catalog: APB03292. | |
| Amifostine Impurity 6 | Amifostine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: S-(2-((3-aminopropyl)amino)ethyl) O,O-diethyl phosphorothioate. Molecular Formula: C9H23N2O3PS. Mole Weight: 270.33. Catalog: APB03291. | |
| Amifostine Impurity 7 | Amifostine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: S-(2-((3-aminopropyl)amino)ethyl) O,O-dimethyl phosphorothioate. Molecular Formula: C7H19N2O3PS. Mole Weight: 242.28. Catalog: APB03293. | |
| Amifostine Impurity 8 | Amifostine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: S-(2-((3-aminopropyl)amino)ethyl) O,O-diisopropyl phosphorothioate. Molecular Formula: C11H27N2O3PS. Mole Weight: 298.38. Catalog: APB03290. | |
| Amifostine Impurity 9 | Amifostine Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N1-(2-bromoethyl)propane-1,3-diamine dihydrobromide. CAS No. 23545-42-8. Molecular Formula: C5H13BrN2·2HBr. Mole Weight: 342.90. Catalog: APB23545428. | |
| Amifostine thiol | Amifostine Thiol is a metabolite of Amifostine. Amifostine thiol activates p53 through a JNK-dependent signaling pathway. Synonyms: 2-[(3-Aminopropyl)amino]-ethanethiol; N-(2-Mercaptoethyl)-1,3-diaminopropane; NSC 647527; WR 1065. Grades: 95%. CAS No. 31098-42-7. Molecular formula: C5H14N2S. Mole weight: 134.25. | |
| Amifostine Thiol Dihydrochloride | A metabolite of Amifostine. Group: Biochemicals. Alternative Names: 2-[ (3-Aminopropyl) amino]ethanethiol Hydrochloride; WR 1065. Grades: Highly Purified. CAS No. 14653-77-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Amifostine Thiol Dihydrochloride-d4 | Amifostine Thiol Dihydrochloride-d4 is the isotope labelled analog of Amifostine Thiol Dihydrochloride, which is a metabolite of amifostine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C5H12D4Cl2N2S, Molecular Weight: 211.19. US Biological Life Sciences. | Worldwide |
| Amifostine trihydrate | Amifostine trihydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 112901-68-5. Pack Sizes: 50mg, 100mg. Molecular Formula: C5H21N2O6PS. US Biological Life Sciences. | Worldwide |
| Amifostine trihydrate | Amifostine trihydrate (WR2721 trihydrate) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine trihydrate selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine trihydrate is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine trihydrate protects cells from damage by scavenging oxygen-derived free radicals. Amifostine trihydrate reduces renal toxicity and has antiangiogenic action [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR2721 trihydrate. CAS No. 112901-68-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0639A. | |
| Amifostine Trihydrate | Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin. Synonyms: Amifostine hydrate. Grades: >98%. CAS No. 112901-68-5. Molecular formula: C5H15N2O3PS.3H2O. Mole weight: 268.27. | |
| 2- (3- ( (2- (Tritylthio) ethyl) amino) propyl) isoindoline-1, 3-dione-d6 | 2- (3- ( (2- (Tritylthio) ethyl) amino) propyl) isoindoline-1, 3-dione-d6 is an intermediate in the synthesis of Amifostine Thiol Dihydrochloride-d6 (A576823), which is a metabolite of amifostine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C32H24D6N2O2S. US Biological Life Sciences. | Worldwide |
| 2-[(3-Aminopropyl)-amino]ethanethiol dihydrogen phosphate | 2-[(3-Aminopropyl)-amino]ethanethiol dihydrogen phosphate. Group: Biochemicals. Alternative Names: Amifostine; Phosphorothioic acid S-[2-[ (3-aminopropyl) amino]ethyl]ester; Ethiofos. Grades: Highly Purified. CAS No. 20537-88-6. Pack Sizes: 1g, 2g, 5g. Molecular Formula: C5H15N2O3PS. US Biological Life Sciences. | Worldwide |
| 2- (3-Aminopropylamino) ethanol | 2- (3-Aminopropylamino) ethanol is the hydroxy analogue of WR-1065 (A576820), a metabolite of Amifostine (A576810). Amifostine is an organic thiophosphate that has the ability to protect a broad range of tissues from cytotoxicity (e.g. from chemotherapeutic agents) without inducing an antitumour response. 2- (3-Aminopropylamino) ethanol is also used as an nucleophilic tag in the detection of human butyrylcholinesterase adducts. Group: Biochemicals. Grades: Highly Purified. CAS No. 4461-39-6. Pack Sizes: 1g, 5g. Molecular Formula: C5H14N2O. US Biological Life Sciences. | Worldwide |
| 2-(3-Aminopropylamino)ethanol | 2-(3-Aminopropylamino)ethanol is the hydroxy analogue of WR-1065, a metabolite of Amifostine. Amifostine is an organic thiophosphate that has the ability to protect a broad range of tissues from cytotoxicity (e.g. from chemotherapeutic agents) without inducing an antitumour response. 2-(3-Aminopropylamino)ethanol is also used as an nucleophilic tag in the detection of human butyrylcholinesterase adducts. Group: Amino alcohols. Alternative Names: Ethanol, 2-[(3-aminopropyl)amino]-;1,3-DIAMINO-N-(2-HYDROXYETHYL)-PROPANE;N-(2-Hydroxyethyl)-1,3-Propanediamine. CAS No. 4461-39-6. Molecular formula: C5H14N2O. Mole weight: 118.18. Appearance: Clear, colorless liquid. Density: 1.0074. Catalog: ACM4461396. |  |
| 2-(Tritylthio)ethanamine | 2-(Tritylthio)ethanamine is an intermediate in the synthesis of Amifostine Thiol Dihydrochloride-d6 (A576823), which is a metabolite of amifostine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1095-85-8. Pack Sizes: 50mg, 250mg. Molecular Formula: C21H21NS. US Biological Life Sciences. | Worldwide |
| WR 1065 | WR 1065 is a metabolite of Amifostine, and a cell-permeable reactive oxygen species scavenger that activates p53 through a JNK-dependent signaling pathway. WR 1065 activates p21waf-1 and MDM2 and inhibits DNA topoisomerase II&alpha. WR 1065 can induce cell cycle arrest and exert cytoprotective activity towards normal cells but not cancer cells in vivo. Synonyms: NSC345308; NSC 345308; NSC-345308; WR1065 Dihydrochloride; WR 1065 Dihydrochloride; WR-1065 Dihydrochloride; 2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride; WR 1065 hydrochloride; Amifostine Thiol Dihydrochloride; WR-1065 dihydrochloride. CAS No. 14653-77-1. Molecular formula: C5H14N2S.2HCl. Mole weight: 207.16. | |
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