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9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Aminacrine. CAS No. 90-45-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-B1422.
9-Aminoacridine
9-aminoacridine appears as yellow needles. Free soluble in alcohol. Group: other material building blocks. Alternative Names: 9-Acridinylamine; 9-Aminoacridine; 9-Aminoacridine free base. CAS No. 90-45-9. Product ID: acridin-9-amine. Molecular formula: 194.23g/mol. Mole weight: C13H10N2. C1=CC=C2C(=C1)C(=C3C=CC=CC3=N2)N. InChI=1S / C13H10N2 / c14-13-9-5-1-3-7-11 (9) 15-12-8-4-2-6-10 (12) 13 / h1-8H, (H2, 14, 15). XJGFWWJLMVZSIG-UHFFFAOYSA-N. 98%.
9-Aminoacridine
9-Aminoacridine is a highly fluorescent dye, an acridine analog. It is used clinically as a topical antiseptic and experimentally as a mutagen. It is an intracellular pH indicator and a DNA intercalating agent. Uses: 9-aminoacridine is used clinically as a topical antiseptic and experimentally as a mutagen. Synonyms: Aminoacridine; NSC 13000; NSC-13000; NSC13000; 10-Amino-5-azaanthracene;9AA;9-Acridinamine;9-Amino-acridin;Acridin-9-amine;Aminacrine. Grades: 98%. CAS No. 90-45-9. Molecular formula: C13H10N2. Mole weight: 194.23.
9-Aminoacridine
Acridine analog. DNA intercalating agent. Group: Biochemicals. Alternative Names: 10-Amino-5-azaanthracene; 9-Aminoacridine; 9AA; Aminacrin; Aminacrine; Izoacridina; Monacrin; NSC 13000; NSC 28747. Grades: Highly Purified. CAS No. 90-45-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
9-Aminoacridine
matrix substance for MALDI-MS, ?99.5% (HPLC). Group: Mass spectrometry (ms).
9-Aminoacridine hydrochloride monohydrate
25g Pack Size. Group: Biochemicals, Organics, Research Organics & Inorganics, Stains & Indicators. Formula: C13H10N2 · HCl · H2O. CAS No. 52417-22-8. Prepack ID 74864563-25g. Molecular Weight 248.71. See USA prepack pricing.
Quinacrine hydrochloride
Quinacrine dihydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. Quinacrine may inhibit the transcription and activity of both basal and inducible nuclear factor-kappaB (NF-kappaB), which may result in the induction of tumor suppressor p53 transcription, the restoration of p53-dependent apoptotic pathways, and tumor cell apoptosis. Continuous NF-kappaB signaling, present in many tumors and in chronic inflammatory processes, promotes the expression of antiapoptotic proteins and cytokines while downregulating the expression of proapoptotic proteins, such as p53. Synonyms: atabrine dihydrochloride; mepacrine dihydrochoride; SN 390. CAS No. 69-05-6. Molecular formula: C23H30ClN3O.2HCl. Mole weight: 472.88.
Tacrine
Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist for the palliative treatment of mild to moderate dementia of the Alzheimer's type. Uses: A centrally acting anticholinesterase and indirect cholinergic agonist. Synonyms: CS 12602, CS 12602, CS 12602; 1,2,3,4-Tetrahydro-5-aminoacridine; 1,2,3,4-tetrahydro-9-acridinamin; 1,2,3,4-tetrahydro-9-amino-acridin; 1,2,3,4-Tetrahydro-9-aminoacridine; 5-Amino-6,7,8,9-tetrahydroacridine; Acridine, 1,2,3,4-tetrahydro-9-amino-; Acridine, 9-amino-1,2,3,4-tetrahydro-. Grades: ≥95%. CAS No. 321-64-2. Molecular formula: C13H14N2. Mole weight: 198.27.
Tacrine hydrochloride
Tacrine hydrochloride is a potent cholinesterase inhibitor used for the treatment of memory deficits in patients with Alzheimers's disease. Tacrine hydrochloride has been shown to inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). Tacrine also inhibits the uptake of serotonin and norepinephrine in rat cerebral cortex and reduces depolarization-induced calcium influx through L-type calcium channels in SN56 neuronal cells. Uses: The treatment of alzheimers's disease. Synonyms: 1,2,3,4-Tetrahydro-5-aminoacridine hydrochloride; Tacrine HCl; Hydroaminacrine; NSC72108; NSC-72108; NSC72108; Tenakrin. Grades: ≥99% by HPLC. CAS No. 1684-40-8. Molecular formula: C13H14N2.HCl. Mole weight: 234.73.
2-Aminoacridin-9(10H)-one hydrochloride
2-Aminoacridin-9(10H)-one hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Amino-9(10H)-acridinone hydrochloride. Product Category: Pyridines. CAS No. 727388-68-3. Molecular formula: C13H11ClN2O. Mole weight: 246.69. Purity: 0.97. Product ID: ACM727388683. Alfa Chemistry ISO 9001:2015 Certified.
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