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| Product | Description | |
|---|---|---|
| Dinactin | A member of the macrotetrolide complex produced by a range of streptomyces species; a monovalent cation ionophore with high selectivity for ammonium and potassium; inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-&gamma. It is also resistant to gram-positive bacteria and mycobacteria. Synonyms: GNF-Pf-90; Antibiotic 170t; NSC63925; 4, 13, 22, 31, 37, 38, 39, 40-Octaoxapentacyclo(32.2.1.17, 10.116, 19.125, 28)tetracontane-3, 12, 21, 30-tetrone, 5,23-diethyl-2,11,14,20,29,32-hexamethyl-(VAN) (8CI). Grades: >95% by HPLC. CAS No. 20261-85-2. Molecular formula: C42H68O12. Mole weight: 764.98. |  |
| Dinactin (Antibiotic AKD 1C, Antibiotic S 3466A) | Dinactin is a member of the macrotetrolide complex produced by a range of Streptomyces species. It is a monovalent cation ionophore with high selectivity for ammonium and potassium. Dinactin inhibited T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-g. Dinactin has not previously been available for intensive investigation. Group: Biochemicals. Alternative Names: Antibiotic AKD 1C, Antibiotic S 3466A. Grades: Highly Purified. CAS No. 20261-85-2. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Monactin | A member of the macrotetrolide complex produced by a range of streptomyces species; a monovalent cation ionophore with high selectivity for ammonium and potassium; inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and IFN-&gamma. It is also resistant to gram-positive bacteria and mycobacteria. Synonyms: 4, 13, 22, 31, 37, 38, 39, 40-Octaoxapentacyclo[32.2.1.17, 10.116, 19.125, 28]tetracontane-3, 12, 21, 30-tetrone, 5-ethyl-2, 11, 14, 20, 23, 29, 32-heptamethyl-, (1R, 2R, 5R, 7R, 10S, 11S, 14S, 16S, 19R, 20R, 23R, 25R, 28S, 29S, 32S, 34S)-; Akd-1B. Grades: >95% by HPLC. CAS No. 7182-54-9. Molecular formula: C41H66O12. Mole weight: 750.95. | |
| Monactin (5-demethyl-5-ethylnonactin, Antibiotic AKD 1B) | Monactin is a member of the macrotetrolide complex produced by a range of Streptomyces species. Unlike nonactin, monactin has not previously been available for intensive investigation. Early literature reported that the related dinactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Monactin inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-gamma. Group: Biochemicals. Alternative Names: 5-demethyl-5-ethylnonactin, Antibiotic AKD 1B. Grades: Highly Purified. CAS No. 7182-54-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Nonactin | Nonactin is a macrotetrolide antibiotic and mitochondrial uncoupler with antibacterial, insecticidal, and acaricidal activities. Nonactin acts as an ionophore for monovalent cations, including K + , and NH 4 + , and it can also inhibit the surface expression of endogenous HSP60. In addition, Nonactin can induce apoptosis in β-catenin mutant tumor cells and has anti-tumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Ammonium ionophore I. CAS No. 6833-84-7. Pack Sizes: 5 mg. Product ID: HY-N6790. |  |
| Nonactin | Nonactin is the smallest member of the macrotetrolide complex produced by a range of Streptomyces species. Originally the name, nonactin, reflected the lack of biological activity. The literature is somewhat confusing in this respect, as virtually all sources of nonactin are contaminated with small amounts of the much more active monactin. The BioAustralis nonactin has been purifed to remove traces of other biologically-active macrotetrolides. Like the other macrotetrolides, nonactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Group: Biochemicals. Grades: Highly Purified. CAS No. 6833-84-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Nonactin | The smallest member of the macrotetrolide complex produced by a range of streptomyces species; a monovalent cation ionophore with high selectivity for ammonium and potassium. It is resistant to gram-positive bacteria, mycobacteria and fungi, and it also inhibits L cells. Synonyms: Werramycin-A; NSC 52141; BRN 0076434; 4, 13, 22, 31, 37, 38, 39, 40-Octaoxapentacyclo(32.2.1.17, 10.116, 19.125, 28)tetracontane-3, 12, 21, 30-tetrone, 2,5,11,14,20,23,29,32-octamethyl-(8CI). Grades: >99% by HPLC. CAS No. 6833-84-7. Molecular formula: C40H64O12. Mole weight: 736.93. | |
| Tetranactin | It is a member of the macrotetrolide complex produced by a range of streptomyces sp. It is a monovalent cation ionophore with high selectivity for ammonium and potassium. Unlike the other macrotetrolides, tetranactin exhibits potent insecticidal activity. It is a glycoprotein transportation inhibitor, an immunosuppressant, an antiproliferative and an antiallergic agent. Synonyms: 5,14,23,32-Tetrademethyl-5,14,23,32-tetraethylnonactin; S-3466-C; 4, 13, 22, 31, 37, 38, 39, 40-Octaoxapentacyclo[32.2.1.17, 10.116, 19.125, 28]tetracontane-3, 12, 21, 30-tetrone, 5,14,23,32-tetraethyl-2,11,20,29-tetramethyl-, (1R, 2R, 5R, 7R, 10S, 11S, 14S, 16S, 19R, 20R, 23R, 25R, 28S, 29S, 32S, 34S)-. Grades: >95% by HPLC. CAS No. 33956-61-5. Molecular formula: C44H72O12. Mole weight: 793.04. | |
| Tetranactin | Tetranactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp. Like the other members of the macrotetrolide family, tetranactin is thought to act as a monvalent cation ionophore with high selectivity for ammonium and potassium. Unlike the other macrotetrolides, tetranactin is reported to exhibit potent insecticidal activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 33956-61-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Trinactin | Trinactin is a tetracyclic lactone compound produced by Streptomyces. It is a monovalent cation ionophore with high selectivity to ammonium and potassium. It can inhibit the proliferation of T cells induced by IL-2, and inhibit the production of cytokines at nanomolar levels of IL-2, IL-4, IL-5 and interferon-&gamma. Synonyms: AKD-1D; S 3466B. Grades: >95% by HPLC. CAS No. 7561-71-9. Molecular formula: C43H70O12. Mole weight: 779.0. | |
| Trinactin (Antibiotic AKD-1D, Antibiotic S 3466B) | Trinactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp. Early literature reported that trinactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Trinactin inhibited T-cell proliferation induced by IL-2 and cytokine production at nonomolar levels for IL-2, IL-4, IL-5 and interferon-gamma. Trinactin has not previously been available for intensive investigation. Group: Biochemicals. Alternative Names: Antibiotic AKD-1D, Antibiotic S 3466B. Grades: Highly Purified. CAS No. 7561-71-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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