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Amsacrine is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II. Synonyms: AMSA; m-AMSA; CI 880, CI880, CI-880; SN-11841; SN 11841; SN11841; acridinyl anisidide. Grades: >98%. CAS No. 51264-14-3. Molecular formula: C21H19N3O3S. Mole weight: 393.46.
Amsacrine
Amsacrine (m-AMSA; acridinyl anisidide) is an inhibitor of topoisomerase II , and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: m-AMSA; acridinyl anisidide. CAS No. 51264-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13551.
Amsacrine hydrochloride
Amsacrine hydrochloride is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II. Uses: Antineoplastic agents. Synonyms: AMSA hydrochloride; m-AMSA hydrochloride; CI-880 hydrochloride; SN-11841 hydrochloride; CI 880 hydrochloride; SN 11841 hydrochloride; CI880 hydrochloride; SN11841 hydrochloride; acridinyl anisidide hydrochloride. Grades: >98%. CAS No. 54301-15-4. Molecular formula: C21H20ClN3O3S. Mole weight: 429.92.
Amsacrine hydrochloride
Amsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II , and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: m-AMSA hydrochloride; acridinyl anisidide hydrochloride. CAS No. 54301-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13551A.
Amsacrine Impurity C
Amsacrine Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Acridin-9(10H)-one. CAS No. 758-95-0. Molecular Formula: C13H9NO. Mole Weight: 195.22. Catalog: APB758950.
Aclarubicin A
Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. It intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. It has potent antineoplastic activity. It is used in the treatment of cancer. It can induce histone eviction from chromatin upon intercalation. It has been listed. Uses: Aclarubicin has potent antineoplastic activity. it is used in the treatment of cancer. it can induce histone eviction from chromatin upon intercalation. Synonyms: 11-Dioxo-4-((2,3,6-trideoxy-4-o-(2,6-dideoxy-4-o-((2r-trans)-tetrahydro-6-met;1-naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6;(1R,2R,4S)-methyl 4-(((2R,5S,6S)-4-(dimethylamino)-5-(((2S,4S,5S,6S)-4-hydroxy-6-methyl-5-(((2R,6S). Grades: ≥95%. CAS No. 57576-44-0. Molecular formula: C42H53NO15. Mole weight: 811.88.
Aclarubicin hydrochloride
Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Synonyms: Aclacinon; Aclaplastin; Aclacinomycin A Hydrochloride; Aclarubicin HCl; Aclarubicina Clorhidrato [Spanish]. Grades: >98%. CAS No. 75443-99-1. Molecular formula: C42H54ClNO15. Mole weight: 848.33.
Amsalog
Asulacrine isethionate is the isethionate salt of an amsacrine analogue with antineoplastic properties. Asulacrine inhibits the enzyme topoisomerase ll, thereby blocking DNA replication and RNA and protein synthesis. Synonyms: Asulacrine isethionate; CI-921. CAS No. 80841-48-1. Molecular formula: C26H30N4O8S2. Mole weight: 590.67.
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