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2'-O-(tert-Butyldimethylsilyl)-6α-hydroxy 7-epi-Paclitaxel is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Uses: 6α-hydroxypaclitaxel derivative. Synonyms: (3xi, 5beta, 6alpha, 7alpha, 10beta, 13alpha)-4, 10-Bis(acetyloxy)-13-{[(2R, 3S)-3-benzamido-2-{[tert-butyl(dimethyl)silyl]oxy}-3-phenylpropanoyl]oxy}-1, 6, 7-trihydroxy-9-oxo-5, 20-epoxytax-11-en-2-yl benzoate; 2-tert-Pentylcyclopentanon; 2-(1,1-dimethyl-propyl)-cyclopentan-1-one; 2'-NOR THIAMINE; 2-t-Amyl-cyclopentanon; (2aR, 3S, 4S, 4aS, 6S, 9S, 11S, 12S, 12aR, 12bS)-9-(((2R, 3S)-3-benzamido-2-((tert-butyldimethylsilyl)oxy)-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-3, 4, 11-trihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-d3, 4]benzo[1, 2-b]oxete-6, 12b-diyl diacetate. Grades: > 98%. CAS No. 165065-08-7. Molecular formula: C53H65NO15Si. Mole weight: 984.16.
Maltitol Solution
Maltitol Solution. CAS No. 9053-46-7. Product ID: PE-0490. Category: Suspension aid; Sweetener. Product Keywords: Sweeteners Excipients; Suspending Agents; PE-0490; Maltitol Solution; Suspension aid; Sweetener; ; 9053-46-7. UNII: NA. Chemical Name: Maltitol solution. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: Candies. Stability and Storage Conditions: Spitol solution can be stable for at least two years at room temperature and pH3~9. However, when stored at 50°C, pH2 for 3 months, there is 1.2% hydrolysis, and the color turns yellow. At pH3, the discoloration was not significant despite hydrolysis (0.2%) under the same storage conditions. At pH4~9, although under alkaline conditions, there is a slight yellowing, but not hydrolysis. Maltitol solutions should be supplemented with antibacterial preservatives, such as sodium benzoate or a mixture with hydroxybenzene. Maltitol solution is non-crystalline. Maltitol solution should be stored in an airtight container and kept in a cool, dry place. Source and Preparation: Maltitol is produced by hydrogenation of high concentration maltitol liquid resulting from amylysis. The resulting maltitol solution contains hydrogenated homologues of oligosaccharides in the raw sugar solution. Applications: Maltitol solution can be used alone or in combination with other excipients such as sorbitol as a sweetener in the prescription of oral pharmaceutical…
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