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A heme-thiolate protein (cytochrome P-450). The enzyme is involved in the biosynthesis of the triterpenoid saponin glycyrrhizin in the plant Glycyrrhiza uralensis (licorice). The enzyme from the plant Medicago truncatula can also hydroxylate β-amyrin. Group: Enzymes. Synonyms: CYP72A; CYP72A154. Enzyme Commission Number: EC 1.14.13.173. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0771; 11-oxo-β-amyrin 30-oxidase; EC 1.14.13.173; CYP72A; CYP72A154. Cat No: EXWM-0771.
alfa-Amyrin
Cas No. 638-95-9.
α-Amyrin
α-Amyrin is a pentacyclic triterpenoid compound with oral activity. α-Amyrin activates the ERK and GSK-3β signaling pathways. α-Amyrin can be used in the study of metabolic syndrome induced by high fructose diet and cognitive dysfunction caused by low cholinergic neurotransmission [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 638-95-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N8423.
α-Amyrin acetate
α-Amyrin acetate, a natural triterpenoid, has anti-inflammatory activity, antispasmodic profile and the relaxant effect [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 863-76-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2842.
α-amyrin synthase
A multifunctional enzyme which produces both α- and β-amyrin (see EC 5.4.99.39, β-amyrin synthase). Group: Enzymes. Synonyms: 2,3-oxidosqualene α-amyrin cyclase; mixed amyrin synthase. Enzyme Commission Number: EC 5.4.99.40. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5582; α-amyrin synthase; EC 5.4.99.40; 2,3-oxidosqualene α-amyrin cyclase; mixed amyrin synthase. Cat No: EXWM-5582.
α-seco-amyrin synthase
The enzyme from Arabidopsis thaliana is multifunctional and produces about equal amounts of α- and β-seco-amyrin. See EC 5.4.99.54, β-seco-amyrin synthase. Group: Enzymes. Enzyme Commission Number: EC 5.4.99.52. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5595; α-seco-amyrin synthase; EC 5.4.99.52. Cat No: EXWM-5595.
b-Amyrin
b-Amyrin. Group: Biochemicals. Alternative Names: 12-Oleanen-3-beta-ol. Grades: Highly Purified. CAS No. 559-70-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C30H50O. US Biological Life Sciences.
Worldwide
β-Amyrin
β-Amyrin. Group: Biochemicals. Alternative Names: Olean-12-en-3 β-ol (6CI,8CI); (+)- β-Amyrin; 3 β-Hydroxyolean-12-ene; NSC 527971; β-Amirin; β-Amyrenol; β-Amyrine. Grades: Highly Purified. CAS No. 559-70-6. Pack Sizes: 5mg. Molecular Formula: C30H50O, Molecular Weight: 426.72. US Biological Life Sciences.
Worldwide
β-Amyrin
β-Amyrin shows effectively counteract amyloid β (Aβ)-induced impairment of long-term potentiation (LTP). β-Amyrin is a promising candidate for Alzheimer's disease (AD) research. β-Amyrin exhibits anti-inflammatory effects, protective activity against pulmonary fibrosis, and notable antibacterial capabilities. β-Amyrin is an orally active natural triterpenoid compound [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 559-70-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2922.
β-amyrin 11-oxidase
Requires cytochrome P-450. Part of the glycyrrhizin biosynthesis pathway. The enzyme is also able to oxidize 30-hydroxy-β-amyrin to 11α,30-dihydroxy-β-amyrin but this is not thought to be part of glycyrrhizin biosynthesis. Group: Enzymes. Synonyms: CYP88D6. Enzyme Commission Number: EC 1.14.13.134. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0733; β-amyrin 11-oxidase; EC 1.14.13.134; CYP88D6. Cat No: EXWM-0733.
β-amyrin 24-hydroxylase
A heme-thiolate protein (P-450). Group: Enzymes. Synonyms: sophoradiol 24-hydroxylase; CYP93E1. Enzyme Commission Number: EC 1.14.99.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1053; β-amyrin 24-hydroxylase; EC 1.14.99.43; sophoradiol 24-hydroxylase; CYP93E1. Cat No: EXWM-1053.
β-amyrin 28-monooxygenase
The enzyme, found in plants, is involved in the biosynthesis of oleanane-type triterpenoids, such as ginsenoside Ro. The enzyme from Medicago trunculata (CYP716A12) can also convert α-amyrin and lupeol to ursolic acid and betulinic acid, respectively. Group: Enzymes. Synonyms: CYP716A52v2; CYP716A12; β-amyrin 28-oxidase. Enzyme Commission Number: EC 1.14.13.201. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0803; β-amyrin 28-monooxygenase; EC 1.14.13.201; CYP716A52v2; CYP716A12; β-amyrin 28-oxidase. Cat No: EXWM-0803.
β-Amyrin acetate
β-Amyrin acetate is a triterpenoid with potent anti-inflammatory, antifungal, anti-diabetic, anti-hyperlipidemic activities. β-Amyrin acetate can inhibit HMG-CoA reductase activity by locating in the hydrophobic binding cleft of HMG CoA reductase [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1616-93-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2923.
beta-Amyrin benzoate
Cas No. 3607-93-0. Molecular formula: C37H54O2. Mole weight: 530.82.
β-amyrin synthase
Some organism possess a monofunctional β-amyrin synthase, other have a multifunctional enzyme that also catalyses the synthesis of α-amyrin (EC 5.4.99.40) or lupeol (EC 5.4.99.41). Group: Enzymes. Synonyms: 2,3-oxidosqualene β-amyrin cyclase; AsbAS1; BPY; EtAS; GgbAS1; LjAMY1; MtAMY1; PNY; BgbAS. Enzyme Commission Number: EC 5.4.99.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5580; β-amyrin synthase; EC 5.4.99.39; 2,3-oxidosqualene β-amyrin cyclase; AsbAS1; BPY; EtAS; GgbAS1; LjAMY1; MtAMY1; PNY; BgbAS. Cat No: EXWM-5580.
β-seco-amyrin synthase
The enzyme from Arabidopsis thaliana is multifunctional and produces about equal amounts of α- and β-seco-amyrin. See EC 5.4.99.52, α-seco-amyrin synthase. Group: Enzymes. Enzyme Commission Number: EC 5.4.99.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5597; β-seco-amyrin synthase; EC 5.4.99.54. Cat No: EXWM-5597.
Δ-amyrin synthase
The enzyme from tomato (Solanum lycopersicum) gives 48% Δ-amyrin, 18% α-amyrin, 13% β-amyrin and traces of three or four other triterpenoid alcohols. See also EC 5.4.99.40, α-amyrin synthase and EC 5.4.99.39, β-amyrin synthase. Group: Enzymes. Synonyms: SlTTS2 (gene name). Enzyme Commission Number: EC 5.4.99.55. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5598; Δ-amyrin synthase; EC 5.4.99.55; SlTTS2 (gene name). Cat No: EXWM-5598.
camelliol C synthase
The product is 97% camelliol, 2% achilleol A and 0.2% β-amyrin. Achilleol is an isomer of camelliol C with a 4-methylenecyclohexanol ring system. This enzyme probably evolved from EC 5.4.99.39, β-amyrin synthase. Group: Enzymes. Synonyms: CAMS1; LUP3 (gene name). Enzyme Commission Number: EC 5.4.99.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5579; camelliol C synthase; EC 5.4.99.38; CAMS1; LUP3 (gene name). Cat No: EXWM-5579.
Diammonium glycyrrhizinate
Diammonium glycyrrhizinate is a salt of glycyrrhetinic acid, a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice. It is effective in the treatment of peptic ulcer and also has expectorant (antitussive) properties. It has some additional pharmacological properties including antiviral, antifungal, antiprotozoal, and antibacterial activities. Uses: Antiviral, antifungal, antiprotozoal, and antibacterial. Synonyms: (3β,20β)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-glucopyranuronosyl-α-D-glucopyranosiduronic Acid Diammonium Salt; 18β-Glycyrrhizic Acid Diammonium Salt; Glycyrrhizic Acid Diammonium Salt; (2S, 3S, 4S, 5R, 6R)-6-(((2S, 3R, 4S, 5S, 6S)-6-Carboxy-2-(((3S, 4aR, 6aR, 6bS, 8aS, 11S, 12aR, 14aR, 14bS)-11-carboxy-4, 4, 6a, 6b, 8a, 11, 14b-heptamethyl-14-oxo-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 14, 14a, 14b-icosahydropicen-3-yl)oxy)-4, 5-dihydroxytetrahydro-2H-pyran-3-yl)oxy)-3, 4, 5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid Diammonia Salt; 18α-Diammonium glycyrrhizinate. Grades: >98%. CAS No. 79165-06-3. Molecular formula: C42H68N2O16. Mole weight: 856.99.
germanicol synthase
The enzyme produces germanicol, β-amyrin and lupeol in the ratio 63:33:4. Group: Enzymes. Synonyms: RsM1; (S)-2,3-epoxysqualene mutase (cyclizing, germanicol-forming). Enzyme Commission Number: EC 5.4.99.34. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5575; germanicol synthase; EC 5.4.99.34; RsM1; (S)-2,3-epoxysqualene mutase (cyclizing, germanicol-forming). Cat No: EXWM-5575.
lupan-3β,20-diol synthase
The reaction occurs in the reverse direction. The recombinant enzyme from Arabidopsis thaliana gives a 1:1 mixture of lupeol and lupan-3β,20-diol with small amounts of β-amyrin, germanicol, taraxasterol and ψ-taraxasterol. See EC 5.4.99.41 (lupeol synthase). Group: Enzymes. Synonyms: LUP1 (gene name). Enzyme Commission Number: EC 4.2.1.128. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4969; lupan-3β,20-diol synthase; EC 4.2.1.128; LUP1 (gene name). Cat No: EXWM-4969.
lupeol synthase
Also forms some β-amyrin. The recombinant enzyme from Arabidopsis thaliana gives a 1:1 mixture of lupeol and lupan-3β,20-diol with small amounts of β-amyrin, germanicol, taraxasterol and ψ-taraxasterol. See EC 4.2.1.128 (lupan-3β,20-diol synthase). Group: Enzymes. Synonyms: LUPI; BPW; RcLUS. Enzyme Commission Number: EC 5.4.99.41. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5583; lupeol synthase; EC 5.4.99.41; LUPI; BPW; RcLUS. Cat No: EXWM-5583.
taraxerol synthase
The enzyme gives taraxerol, β-amyrin and lupeol in the ratio 70:17:13. Group: Enzymes. Synonyms: RsM2; (S)-2,3-epoxysqualene mutase (cyclizing, taraxerol-forming). Enzyme Commission Number: EC 5.4.99.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5576; taraxerol synthase; EC 5.4.99.35; RsM2; (S)-2,3-epoxysqualene mutase (cyclizing, taraxerol-forming). Cat No: EXWM-5576.
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