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Andrographolide is a labdane diterpenoid. Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata. Andrographolide showed significant antihepatotoxic action in P. berghei K173- induced hepatic damage in M. natalensis. Andrographolide inhibits tumor necrosis factor-α (TNF-α)-induced intercellular adhesion mol.-1 (ICAM-1) expression and adhesion of HL-60 cells onto human umbilical vein endothelial cells (HUVEC), which are associated with inflammatory diseases. These findings suggest that Andrographolide may have potential as a cardiovascular-protective agent. Group: Biochemicals. Alternative Names: (3E, 4S) -3- [2- [ (1R, 4aS, 5R, 6R, 8aS) -Decahydro-6-hydroxy-5- (hydroxymethyl) -5, 8a-dimethyl-2-methylene-1-naphthalenyl] ethylidene] dihydro-4-hydroxy-2 (3H) -furanone; [1R-[1α[E(S*)],4a β , 5α , 6α , 8aα ] ] -3- [2- [Decahydro-6-hydroxy-5- (hydroxymethyl) -5, 8a-dimethyl-2-methylene-1-naphthalenyl] ethylidene] dihydro-4-hydroxy-2 (3H) -furanone; 3α,14,15,18-Tetrahydroxy-5 β,9 βH,10α-labda-8(20),12-dien-16-oic Acid γ-Lactone; Andrographis; Andrographolid. Grades: Highly Purified. CAS No. 5508-58-7. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Andrographolide
Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects. Group: Inhibitors. Alternative Names: 2(3H)-Furanone,3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-met. CAS No. 5508-58-7. Molecular formula: C20H30O5. Mole weight: 350.45. Appearance: White powder. Purity: 0.98. IUPACName: (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one. Canonical SMILES: C[C@@]12CC[C@H] ([C@@] ([C@H]1CCC (=C)[C@H]2C/C=C/3\[C@@H] (COC3=O)O) (C)CO)O. Density: 1.23 g/ml. Catalog: ACM5508587.
Andrographolide
Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects. Uses: Scientific research. Group: Natural products. Alternative Names: Andrographis. CAS No. 5508-58-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0191.
Andrographolide
Andrographolide - Product ID: NST-10-72. Category: Terpenes. Purity: 98%. Test method: HPLC. CAS No. 5508-58-7. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: White to beige coloured Powder. Molecular formula: C20H30O5. Mole weight: 350.45. Storage: +2 +8 °C.
14-Deoxy-11,12-didehydroandrographolide
14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation. Uses: Scientific research. Group: Natural products. Alternative Names: 14-dehydro Andrographolide; AP10. CAS No. 42895-58-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N1490.
Dehydroandrographolide
Dehydroandrographolide is a natural diterpenoid found in Andrographis paniculata. It possesses activity against hepatitis B virus DNA replication. Uses: Dehydroandrographolide is a natural diterpenoid found in andrographis paniculata and possesses activity against hepatitis b virus dna replication. Synonyms: Andrographolide, dehydro-; Deoxy-11,12-didehydroandrographolide; (3E)-3-[2-[(1S,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-2(3H)-furanone; 14-Deoxy-11-dehydroandrographolide. Grades: >98%. CAS No. 134418-28-3. Molecular formula: C20H28O4. Mole weight: 332.43.
2,6-Dichloronicotinyl Chloride
2,6-Dichloronicotinyl Chloride is a reactant used in the preparation of semisynthetic derivatives of andrographolide and inhibitors of hepatitis C (HCV) NS5B polymerase. Group: Biochemicals. Alternative Names: 2,6-Dichloronicotinoyl Chloride; 2,6-Dichloropyridine-3-carbonyl Chloride. Grades: Highly Purified. CAS No. 58584-83-1. Pack Sizes: 500mg, 5g. US Biological Life Sciences.
Worldwide
Andrographis Extract (Standard)
Andrographis paniculata belongs to Acanthaceae. It is an annual herb and harvested in autumn. It originates from India and now widely cultivated in Yunnan, Guangdong, Guangxi Hainan, Fujian, etc. Applications: Treating & preventing colds: taking andrographis may help to reduce the severity of your symptoms from the common cold.supporting the immune system: andrographis may stimulate the immune response and support the immune system.treating infections: andrographis's immunity-boosting constituents may also help to fight certain infections.treating gastrointestinal ailments: the andrographolides contained in andrographis may also help to treat certain gastrointestinal problems by stimulating the secretion of bile. Group: Others. CAS No. 5508-58-7. Purity: 50.0% Andrographolide HPLC. Mole weight: 350.44. Andrographis Extract (Standard); 5508-58-7; C20H30O5. Cat No: EXTW-013.
Andrographis Paniculata Extract
Andrographis paniculata extract is derived form the plant of andrographis paniculata. This ancient chinese medicinal herb known as chuaxinlian is historically been used as a hepatoprotective and for common cold. Andrographis extract is used as a bitter ingredient in the chinese indigenous system of medicine. And andrographis paniculata extract is useful in intermittent fevers. The major active ingredient is andrographolides. Group: Others. Mole weight: 350.45. Andrographis Paniculata Extract; Andrographis Paniculata (burm. F.) Nees. Cat No: EXTC-041.
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