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| Product | Description | |
|---|---|---|
| Androstenedione 16,17'-Anhydro Dimer | Androstenedione 16,17'-Anhydro Dimer. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 5MG. Catalog: APS005765. Format: Neat. Shipping: Room Temperature. |  |
| 11 β-Hydroxyandrostenedione Glucuronide | 11 β-Hydroxyandrostenedione Glucuronide is a metabolite of Androstenedione (A637550), a testosterone precursor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C25H34O9, Molecular Weight: 478.53. US Biological Life Sciences. |  Worldwide |
| 11 β-Hydroxyandrostenedione Sulphate | 11 β-Hydroxyandrostenedione Sulphate is a metabolite of Androstenedione (A637550), a testosterone precursor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C19H26O6S, Molecular Weight: 382.47. US Biological Life Sciences. | Worldwide |
| 6,7,15,16-Dimethylene-4-ene-3,17-androstenedione | Heterocyclic Organic Compound. Alternative Names: 1H-Dicyclopropa[6, 7:15, 16]cyclopenta[a]phenanthrene-3, 17(2H, 10H)-dione;6, 7, 15, 16-Dimethylene-4-ene-3, 17-androstenedione. CAS No. 116298-21-6. Molecular formula: C21H26O2. Mole weight: 310.43. Density: 1.22. Catalog: ACM116298216. |  |
| 6a-Bromo androstenedione | 6a-Bromo androstenedione. Group: Biochemicals. Alternative Names: (6a)-6-Bromoandrost-4-ene-3,17-dione. Grades: Highly Purified. CAS No. 61145-67-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C19H25BrO2. US Biological Life Sciences. | Worldwide |
| 6α-Bromo Androstenedione | Androstenedione analog, an aromatase inhibitor. Group: Biochemicals. Alternative Names: (6α)-6-Bromoandrost-4-ene-3,17-dione. Grades: Highly Purified. CAS No. 61145-67-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 6 β-Bromo Androstenedione | Androstenedione analog, an aromatase inhibitor. Group: Biochemicals. Alternative Names: (6 β)-6-Bromoandrost-4-ene-3,17-dione. Grades: Highly Purified. CAS No. 38632-00-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (7α)-Methyl Androstenedione 3-Ethylene Ketal | Mibolerone intermediate. Group: Biochemicals. Alternative Names: (7α)-7-Methyl-estr-5(10)-ene-3,17-dione Cyclic 3-(1,2-Ethanediyl Acetal). Grades: Highly Purified. CAS No. 141664-12-2. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Δ1-Androstenedione | Δ1-Androstenedione as a prodrug of Δ1-Testosterone. Group: Biochemicals. Grades: Highly Purified. CAS No. 571-40-4. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H26O2. US Biological Life Sciences. | Worldwide |
| 17α-hydroxyprogesterone deacetylase | A microsomal cytochrome P-450 (heme-thiolate) protein that catalyses two independent reactions at the same active site - the 17-hydroxylation of pregnenolone and progesterone, which is part of glucocorticoid hormones biosynthesis (EC 1.14.14.19), and the conversion of the 17-hydroxylated products via a 17,20-lyase reaction to form androstenedione and 3β-hydroxyandrost-5-en-17-one, leading to sex hormone biosynthesis. The activity of this reaction is dependent on the allosteric interaction of the enzyme with cytochrome b5 without any transfer of electrons from the cytochrome. The enzymes from different organisms differ in their substrate specificity. While the enzyme...son do not accept the former, and the enzyme from guinea pig does not accept the latter. Group: Enzymes. Synonyms: C-17/C-20 lyase; 17α-hydroxyprogesterone acetaldehyde-lyase; CYP17; CYP17A1 (gene name); 17α-hydroxyprogesterone 17,20-lyase. Enzyme Commission Number: EC 1.14.14.32. CAS No. 62213-24-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0930; 17α-hydroxyprogesterone deacetylase; EC 1.14.14.32; 62213-24-5; C-17/C-20 lyase; 17α-hydroxyprogesterone acetaldehyde-lyase; CYP17; CYP17A1 (gene name); 17α-hydroxyprogesterone 17,20-lyase. Cat No: EXWM-0930. |  |
| 17-Keto Drospirenone | An intermediate for the production of Drospirenone from Androstenedione. Synonyms: (6R, 7R, 8R, 9S, 10R, 13S, 14S, 15S, 16S)-6, 7, 8, 9, 11, 12, 13, 14, 15, 16, 20, 21-Dodecahydro-10, 13-dimethyl-1H-dicyclopropa[6, 7:15, 16]cyclopenta[a]phenanthrene-3, 17(2H, 10H)-dione. Grades: > 95%. CAS No. 116298-21-6. Molecular formula: C21H26O2. Mole weight: 310.43. |  |
| 2 β-Hydroxy-androst-4-ene-3,17-dione | 2 β-Hydroxy-androst-4-ene-3,17-dione is the microbial oxidation product of Androstenedione (A637550), which is a Testosterone precursor and metabolite with androgenic activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 571-16-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C19H26O3, Molecular Weight: 302.41. US Biological Life Sciences. | Worldwide |
| 2-Bromo 17 β-Estradiol | 17 β-Estradiol (E888000) metabolite. An inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells. Group: Biochemicals. Alternative Names: 2-Bromo-estradiol; 2-Bromo-1,3,5(10)-estratriene-3,17 β-diol; 2-Bromo- β-estradiol; 2-Bromoestradiol; NSC 105460. Grades: Highly Purified. CAS No. 15833-07-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Bromo β-Estradiol 17-Acetate | 2-Bromo β-Estradiol 17-Acetate is an intermediate in synthesizing 2-Bromo 17 β-Estradiol (B684970), an 17 β-Estradiol (E888000) metabolite. Which is an inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1mg. Molecular Formula: C20H25BrO3. US Biological Life Sciences. | Worldwide |
| (4α,?5α)?-Formestane | (4α,?5α)?-Formestane is an isomer of Formestane. Formestane is a type I, steroidal, selective aromatase inhibitor that is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. Formestane is an analogue of androstenedione. It is also used to inhibit the estrogen production. Synonyms: 4-Hydroxyandrostane-3,17-dione; 4-hydroxy-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-dione. CAS No. 848-35-1. Molecular formula: C19H28O3. Mole weight: 304.43. | |
| 4-Bromo 17 β-Estradiol | 17 β-Estradiol (E888000) metabolite. An inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells. Group: Biochemicals. Alternative Names: 4-Bromo-estra-1,3,5(10)-triene-3,17 β-diol; 4-Bromo-1,3,5(10)-estratriene-3,17 β-diol; 4-Bromo-17 β-estradiol; 4-Bromo- β-estradiol; 4-Bromoestradiol; NSC 104802. Grades: Highly Purified. CAS No. 1630-83-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| (9 β,10α)-4-Chloro-Androst-4-ene-3,17-dione | (9 β,10α)-4-Chloro-Androst-4-ene-3,17-dione is an impurity of Androstenedione, a Testosterone precursor and metabolite with androgenic activity. Group: Biochemicals. Alternative Names: Androstenedione Impurity A. Grades: Highly Purified. CAS No. 6765-84-0. Pack Sizes: 500ug. Molecular Formula: C??H??ClO?, Molecular Weight: 320.85. US Biological Life Sciences. | Worldwide |
| Androst-4-ene-3,17-dione-2,2,4,6,6,16,16-d7 | Androst-4-ene-3,17-dione-2,2,4,6,6,16,16-d7 is an intermediate in the synthesis of Dehydroepiandrosterone-d5 which is the labeled analogue of Dehydro Epiandrosterone (D229585). Dehydro Epiandrosterone is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 67034-85-9. Pack Sizes: 50mg, 100mg. Molecular Formula: C19H19D7O2. US Biological Life Sciences. | Worldwide |
| androst-4-ene-3,17-dione monooxygenase | Has a wide specificity. A single enzyme from the ascomycete Neonectria radicicola (EC 1.14.13.54, ketosteroid monooxygenase) catalyses both this reaction and that catalysed by EC 1.14.99.4, progesterone monooxygenase. Group: Enzymes. Synonyms: androstene-3,17-dione hydroxylase; androst-4-ene-3,17-dione 17-oxidoreductase; androst-4-ene-3,17-dione hydroxylase; androstenedione monooxygenase; 4-androstene-3,17-dione monooxygenase. Enzyme Commission Number: EC 1.14.99.12. CAS No. 37256-74-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1033; androst-4-ene-3,17-dione monooxygenase; EC 1.14.99.12; 37256-74-9; androstene-3,17-dione hydroxylase; androst-4-ene-3,17-dione 17-oxidoreductase; androst-4-ene-3,17-dione hydroxylase; androstenedione monooxygenase; 4-androstene-3,17-dione monooxygenase. Cat No: EXWM-1033. | |
| Androstenediol 17-Acetate | Androstenediol 17-Acetate is used in synthetic preparation for direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. Androstenediol 17-Acetate is also obtained from Dehydro Epiandrosterone (D229585) which is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 5937-72-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H32O3, Molecular Weight: 332.48. US Biological Life Sciences. | Worldwide |
| ASP-9521 | ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3). ASP9521 has demonstrated anti-tumour activity in in vitro and in vivo preclinical models. ASP9521 inhibited conversion of androstenedione (AD) into testosterone (T) by recombinant human or cynomolgus monkey AKR1C3 in a concentration-dependent manner. Synonyms: ASP9521; ASP-9521; ASP 9521. AKR1C3 inhibitor ; 17HSD5 inhibitor;4-(2-Hydroxy-2-methylpropyl)piperidino(5-methoxy-1H-indole-2-yl)methanone; 1-[1-[(5-Methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl]-2-methylpropan-2-ol. Grades: 98%. CAS No. 1126084-37-4. Molecular formula: C19H26N2O3. Mole weight: 330.428. | |
| C-19 steroid 1α-hydroxylase | The enzyme, characterized from the bacterium Sorangium cellulosum, is a class I cytochrome P-450, and uses ferredoxin as its electron donor. It was shown to act on several C-19 steroid substrates, including testosterone, androstenedione, testosterone-acetate and 11-oxoandrostenedione. Group: Enzymes. Synonyms: CYP260A1. Enzyme Commission Number: EC 1.14.15.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0944; C-19 steroid 1α-hydroxylase; EC 1.14.15.19; CYP260A1. Cat No: EXWM-0944. | |
| Cyclic 17-(1,2-Ethanediyl Acetal) 3-(Acetyloxy)-androsta-3,5-dien-17-one-d9 | Cyclic 17-(1,2-Ethanediyl Acetal) 3-(Acetyloxy)-androsta-3,5-dien-17-one-d9 is an intermediate in the synthesis of Dehydroepiandrosterone-d5 which is the labeled analogue of Dehydro Epiandrosterone (D229585). Dehydro Epiandrosterone is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C21H19D9O3. US Biological Life Sciences. | Worldwide |
| Cyclic 17-(1,2-Ethanediyl Acetal) Androst-4-ene-3,17-dione | Cyclic 17-(1,2-Ethanediyl Acetal) Androst-4-ene-3,17-dione is an intermediate in the synthesis of Dehydroepiandrosterone-d5 which is the labeled analogue of Dehydro Epiandrosterone (D229585). Dehydro Epiandrosterone is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 1044-89-9. Pack Sizes: 25mg, 250mg. Molecular Formula: C21H30O3. US Biological Life Sciences. | Worldwide |
| Δ4-3-oxosteroid 5β-reductase | The enzyme from human efficiently catalyses the reduction of progesterone, androstenedione, 17α-hydroxyprogesterone and testosterone to 5β-reduced metabolites; it can also act on aldosterone, corticosterone and cortisol, but to a lesser extent. The bile acid intermediates 7α,12α-dihydroxy-4-cholesten-3-one and 7α-hydroxy-4-cholesten-3-one can also act as substrates. Group: Enzymes. Synonyms: 3-oxo-Δ4-steroid 5β-reductase; 5β-reductase; androstenedione 5β-reductase; cholestenone 5β-reductase; cortis. Enzyme Commission Number: EC 1.3.1.3. CAS No. 9029-8-7. 3-oxo-5-beta-steroid 4-dehydrogenase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1303; Δ4-3-oxosteroid 5β-reductase; EC 1.3.1.3; 9029-08-7; 3-oxo-Δ4-steroid 5β-reductase; 5β-reductase; androstenedione 5β-reductase; cholestenone 5β-reductase; cortisone 5β-reductase; cortisone β-reductase; cortisone Δ4-5β-reductase; steroid 5β-reductase; testosterone 5β-reductase; Δ4-3-ketosteroid 5β-reductase; Δ4-5β-reductase; Δ4-hydrogenase; 4,5β-dihydrocortisone:NADP+ Δ4-oxidoreductase; 3-oxo-5β-steroid:NADP+ Δ4-oxidoreductase. Cat No: EXWM-1303. | |
| Δ4-Abiraterone | Δ4-Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone (Item No. 9002768).1 D4A is an androgen receptor antagonist (IC50 = 5.3 nM) that reduces expression of the androgen receptor target genes PSA, TMPRSS2, and FKBP5 in LNCaP, LAPC4, and C4-2 cell lines. It inhibits the cytochrome P450 (CYP) isoform CYP17A1 by 66.5% when used at a concentration of 1 nM. D4A (10 μM) also blocks SRD5A conversion of Δ4-androstenedione to 5α-androstanedione in LAPC4 cells. In vivo, D4A delays tumor progression in a VCaP mouse xenograft model and increases progression-free survival in a C4-2 mouse xenograft model. Synonyms: CB 7627; D4A. Grades: ≥98%. CAS No. 154229-21-7. Molecular formula: C24H29NO. Mole weight: 347.49. | |
| Estrone | Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: E1; Oestrone. CAS No. 53-16-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0234. |  |
| Estrone-d4 | Estrone-d 4 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: E1-d4; Oestrone-d4. CAS No. 53866-34-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0234S2. | |
| ketosteroid monooxygenase | A single FAD-containing enzyme catalyses three types of monooxygenase (Baeyer-Villiger oxidation) reaction. The oxidative esterification of a number of derivatives of progesterone to produce the corresponding 17α-hydroxysteroid 17-acetate ester, such as testosterone acetate, is shown in Reaction (1). The oxidative lactonization of a number of derivatives of androstenedione to produce the 13,17-secoandrosteno-17,13α-lactone, such as testololactone, is shown in Reaction (2). The oxidative cleavage of the 17β-side-chain of 17α-hydroxyprogesterone to produce androstenedione and acetate is shown in Reaction (3). Reaction (1) is also catalysed by EC 1.14.99.4 (p...uctase (20-hydroxylating, side-chain cleaving); androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing). Enzyme Commission Number: EC 1.14.13.54. CAS No. 9044-53-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0861; ketosteroid monooxygenase; EC 1.14.13.54; 9044-53-5; steroid-ketone monooxygenase; progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing); 17α-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving); androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing). Cat No: EXWM-0861. | |
| LX1 | LX1 is an anti-prostate cancer compound that targets androgen receptor ( AR ), AR variants and steroidogenic enzyme AKR1C3. LX1 inhibits the enzymatic activity of AKR1C3 , reduces the conversion of androstenedione to testosterone and reduces the expression of AR and AR-V7 and downregulates their target genes. LX1 overcomes the resistance of tumor cells to Enzalutamide (HY-70002), and the combination with Enzalutamide (HY-70002) further inhibits tumor growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2647877-84-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163940. | |
| Methyl 3,17-Dioxo-4-androsten-19-oate | A methoxy hydroperoxide androstenedione derivative; analog of a potential aromatase intermediate. Group: Biochemicals. Alternative Names: 3,17-Dioxo-androst-4-en-19-oic Acid Methyl Ester. Grades: Highly Purified. CAS No. 22256-03-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| steroid 17α-monooxygenase | Requires NADPH and EC 1.6.2.4, NADPH-hemoprotein reductase. A microsomal hemeprotein that catalyses two independent reactions at the same active site - the 17α-hydroxylation of pregnenolone and progesterone, which is part of glucocorticoid hormones biosynthesis, and the conversion of the 17α-hydroxylated products via a 17,20-lyase reaction to form androstenedione and dehydroepiandrosterone, leading to sex hormone biosynthesis (EC 4.1.2.30, 7α-hydroxyprogesterone aldolase). The ratio of the 17α-hydroxylase and 17,20-lyase activities is an important factor in determining the directions of steroid hormone biosynthesis towards biosynthesis of glucocorticoid or sex hormones. Group: Enzymes. Synonyms: steroid 17α-hydroxylase; cytochrome P-450 17α; cytochrome P-450 (P-450 17α,lyase); 17α-hydroxylase-C17,20 lyase; CYP17; CYP17A1 (gene name). Enzyme Commission Number: EC 1.14.14.19. CAS No. 9029-67-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0916; steroid 17α-monooxygenase; EC 1.14.14.19; 9029-67-8; steroid 17α-hydroxylase; cytochrome P-450 17α; cytochrome P-450 (P-450 17α,lyase); 17α-hydroxylase-C17,20 lyase; CYP17; CYP17A1 (gene name). Cat No: EXWM-0916. | |
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