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| Product | Description | |
|---|---|---|
| Angelicin | Angelicin, a furocoumarin naturally occurring tricyclic aromatic compound, structurally related to psoralens, is reported to have anti-cancer, antiviral, anti-inflammatory activity.IC50 value: 49.56 μM (cellular cytotoxicity); 5.39 μg/ml (28.95 μM) (against MHV-68)Target:In vitro: In human SH-SY5Y neuroblastoma cells, angelicin increased cellular cytotoxicity in a dose- and time-dependent manner with IC50 of 49.56 μM at 48 h of incubation. Angelicin dose-dependently downregulated the expression of anti-apoptotic proteins including Bcl-2, Bcl-xL, and Mcl-1; Angelicin-induced apoptosis is mediated primarily through the intrinsic caspase-mediated pathway. Angelicin efficiently inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced lytic replication of human gammaherpresviruses in both EBV- and KSHV-infected cells. Angelicin was potentially advantageous to prevent inflammatory diseases by inhibiting NF-κB and MAPK pathways.In vivo: Group: Inhibitors. CAS No. 523-50-2. Molecular formula: C11H6O3. Mole weight: 186.16. Appearance: Solid. Purity: 0.9986. Canonical SMILES: O=C1C=CC2=CC=C(OC=C3)C3=C2O1. Catalog: ACM523502. |  |
| Angelicin | Angelicin. Group: Biochemicals. Alternative Names: Furo[2,3-h]chromen-2-one; 2-Oxo-(2H)-furo(2,3-H)-1-benzopyran. Grades: Highly Purified. CAS No. 523-50-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H6O3. US Biological Life Sciences. |  Worldwide |
| Angelicin | Angelicin is a furanocoumarin compound that functions as an inhibitor of NF-κB and MAPK signaling pathways, exhibiting anti-inflammatory, antiviral, and antitumor activities. It suppresses the lytic replication of γ-herpesviruses, such as MHV-68, early during viral infection, potentially inhibiting RTA gene expression ( IC 50 =28.95 μM). Angelicin also mitigates inflammation by inhibiting the phosphorylation and nuclear translocation of NF-κB , and the phosphorylation of p38 and JNK. Furthermore, it induces apoptosis in neuroblastoma cells by downregulating anti-apoptotic proteins like Bcl-2 , Bcl-xL , and Mcl-1 , while activating caspase-9 and caspase-3. Uses: Scientific research. Group: Natural products. Alternative Names: Isopsoralen. CAS No. 523-50-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0763. |  |
| Angelicin (Isopsoralen) | Angelicin (Isopsoralen). Group: Biochemicals. Alternative Names: Isopsoralen; Bakuchicin. Grades: Plant Grade. CAS No. 523-50-2. Pack Sizes: 20mg. Molecular Formula: C11H6O3, Molecular Weight: 186.164. US Biological Life Sciences. | Worldwide |
| angelicin synthase | This P-450 monooxygenase enzyme is involved in the formation of angular furanocoumarins. Attacks its substrate by syn-elimination of hydrogen from C-3'. Group: Enzymes. Synonyms: CYP71AJ4 (gene name). Enzyme Commission Number: EC 1.14.13.115. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0715; angelicin synthase; EC 1.14.13.115; CYP71AJ4 (gene name). Cat No: EXWM-0715. |  |
| Bata-Sitosterol | Bata-Sitosterol. Group: Biochemicals. Alternative Names: beta-Sitosterol; Nimbosterol; Cupreol; Quebrachol; Rhamnol; Cinchol; Verosterol; Slanutosterol; Raphanisterol; Papaveristerol; Sitosterol; Angelicin; 22,23-Dihydrostigmasterol. Grades: Plant Grade. CAS No. 83-46-5. Pack Sizes: 20mg. Molecular Formula: C29H50O, Molecular Weight: 414.706999999999. US Biological Life Sciences. | Worldwide |
| Isopsoralen | Isopsoralen - Product ID: NST-10-169. Category: Coumarins. Alternative Names: 2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, ?-lactone, 2H-Furo[2,3-h]chromen-2-one, Angecin, Angelicin, Furo[2,3-h]coumarin, Furo[5?,4?:7,8]coumarin. Purity: 98%. Test method: HPLC. CAS No. 523-50-2. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White to beige coloured Powder. Molecular formula: C11H6O3. Mole weight: 186.16. Storage: +2 +8 °C. |  |
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