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| Product | Description | |
|---|---|---|
| Anhydroicaritin | β-Anhydroicaritin is an Icartin (I163680) derivative displaying anti-inflammatory activity and inhibition of human phosphodiesterase-5. Synonyms: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one. Grades: >98%. CAS No. 38226-86-7. Molecular formula: C21H20O6. Mole weight: 368.4. |  |
| Anhydroicaritin, β- | Anhydroicaritin, β-. Group: Biochemicals. CAS No. 38226-86-7. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Baohuoside I (Anhydroicaritin, Icariside II) | Baohuoside I (Anhydroicaritin, Icariside II). Group: Biochemicals. Alternative Names: Icariside II. Grades: Plant Grade. CAS No. 113558-15-9. Pack Sizes: 20mg. Molecular Formula: C27H30O10, Molecular Weight: 514.520999999999. US Biological Life Sciences. | Worldwide |
| Β-Anhydroicaritin | β-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties. β-Anhydroicaritin ameliorates the degradation of periodontal tissue and inhibits the synthesis and secretion of TNF-α and MMP-3 in diabetic rats. β-Anhydroicaritin decreases the overproduction of NO, IL-10, TNF-α, MCP-1 and IL-6 in inperitonitis mice. β-Anhydroicaritin inhibits the elevation of intracellular Ca2+, and markedly decreases iNOS protein expression. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 38226-86-7. Molecular formula: C21H20O6. Mole weight: 368.38. Purity: 0.98. Product ID: ACM38226867. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Icaritin (Anhydroicaritin) | Icaritin (Anhydroicaritin). Group: Biochemicals. Grades: Plant Grade. CAS No. 118525-40-9. Pack Sizes: 20mg. Molecular Formula: C21H20O6, Molecular Weight: 368.38. US Biological Life Sciences. | Worldwide |
| Icaritin | Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornu Maxim. and potently inhibits proliferation of K562 cells ( IC 50 of 8 μM) and primary CML cells ( IC 50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis [1] [2] [3. Uses: Scientific research. Group: Natural products. Alternative Names: Anhydroicaritin. CAS No. 118525-40-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0678. |  |
| Icaritin | Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or time-dependent manner. Synonyms: Anhydroicaritin; 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one; 3-hydroxy-7-o-beta-glucose-8-prenyl-4''-methoxy Chrysin. Grades: >98%. CAS No. 118525-40-9. Molecular formula: C21H20O6. Mole weight: 368.38. | |
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