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| Product | Description | |
|---|---|---|
| Anle138b | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Anle138b | Anle138b is a novel fluorescent oligomer modulator and an aggregation inhibitor. In vitro, anle138b blocked the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein. Synonyms: Anle138b; Anle 138b; Anle-138b; 5-(1,3-benzodioxol-5-yl)-3-(3-bromophenyl)-1H-pyrazole; 3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole; anle138b. CAS No. 882697-00-9. Molecular formula: C16H11BrN2O2. Mole weight: 343.17. |  |
| Emrusolmin | Emrusolmin (Anle138b), an oligomeric aggregation inhibitor, blocks the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein (α-syn). Emrusolmin strongly inhibits oligomer accumulation, neuronal degeneration, and disease progression in vivo. Emrusolmin has low toxicity and an excellent oral bioavailability and blood-brain-barrier penetration. Emrusolmin blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Anle138b. CAS No. 882697-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101855. |  |
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