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| Product | Description | |
|---|---|---|
| Anpirtoline hydrochloride | Anpirtoline (D-16949) hydrochloride is a centrally acting 5-HT 1B receptor agonist, with K i s of 28 nM (5-HT 1B ), 150 nM (5-HT 1A ) and 1.49 μM (5-HT2). Anpirtoline hydrochloride has serotonergic, antinociceptive, antidepressant-like effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-16949 hydrochloride. CAS No. 99201-87-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101100. |  |
| Anpirtoline hydrochloride | Anpirtoline hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 99201-87-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Anpirtoline hydrochloride | Anpirtoline hydrochloride is the hydrochloride salt of anpirtoline, which is a highly potent 5-HT1B receptor agonist with Ki values of 28 nM. It decreases central serotonin synthesis and attenuates aggressive behavior in vivo. It also acts as an antagonist at 5-HT3 receptors with Ki value of 29.5 nM and is brain penetrant. It is a receptor agonist with antinociceptive/antidepressant-like actions in rodents. Synonyms: Pyridine, 2-chloro-6-(4-piperidinylthio)-, hydrochloride (1:1); Pyridine, 2-chloro-6-(4-piperidinylthio)-, monohydrochloride; 2-Chloro-6-(piperidin-4-ylsulfanyl)pyridine hydrochloride; 2-Chloro-6-(piperidin-4-ylthio)pyridine hydrochloride; D16949; D-16949; D 16949. Grades: ≥99% by HPLC. CAS No. 99201-87-3. Molecular formula: C10H14Cl2N2S. Mole weight: 265.20. |  |
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