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| Product | Description | |
|---|---|---|
| AP-III-a4 | AP-III-a4, also known as ENOblock, is the first, nonsubstrate inhibitor of enolase, blocking cancer cell metastasis in vivo. biochemical analysis showed that the half maximal inhibitory concentration (IC50) of enolase inhibition by ENOblock is 0.576 μM. ENOblock can inhibit cancer cell metastasis in vivo. Moreover, an unexpected role for enolase in glucose homeostasis was revealed by in vivo analysis. ENOblock is the first reported enolase inhibitor that is suitable for biological assays. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AP-III-a4; ENOblock. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1177827-73-4. Molecular formula: C31H43FN8O3. Mole weight: 594.74. Purity: >98%. IUPACName: N-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]-4-[[4-[(cyclohexylmethyl)amino]-6-[[(4-fluorophenyl)methyl]amino]-1,3,5-triazin-2-yl]amino]benzeneacetamide. Canonical SMILES: O=C(NCCOCCOCCN)CC1=CC=C(NC2=NC(NCC3CCCCC3)=NC(NCC4=CC=C(F)C=C4)=N2)C=C1. Product ID: ACM1177827734. Alfa Chemistry ISO 9001:2015 Certified. |  |
| AP-III-a4 | AP-III-a4 (ENOblock) is a nonsubstrate analogue enolase inhibitor with an IC 50 of 0.576 uM. AP-III-a4 can be used for the research of cancer and diabetic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENOblock. CAS No. 1177827-73-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15858. |  |
| AP-III-a4 | AP-III-a4 is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 μM); inhibit cancer cell metastasis in vivo. Synonyms: ENOblock. Grades: >98%. CAS No. 1177827-73-4. Molecular formula: C31H43FN8O3. Mole weight: 594.72. |  |
| AP-III-a4 hydrochloride | AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC 50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENOblock hydrochloride. CAS No. 2070014-95-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15858A. | |
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