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| Product | Description | |
|---|---|---|
| Apilimod mesylate | Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC 50 s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively [1]. Apilimod is a potent and highly selective PIKfyve inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STA 5326 mesylate; LAM-002A; AIT-101 mesylate. CAS No. 870087-36-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14644A. |  |
| Apilimod mesylate | The mesylate salt form of Apilimod. Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Synonyms: methanesulfonic acid N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grades: 98%. CAS No. 870087-36-8. Molecular formula: C23H26N6O2.2CH4O3S. Mole weight: 610.7. |  |
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