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Apomorphine is an orally active agonist of Dopamine receptor. Apomorphine can be used in study Parkinson, biphasic dyskinesias, urinary dysfunction,,dystonia, dyspnoea, anismus and belching [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Apomorphine. CAS No. 58-00-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-12723.
Apomorphine-[13C,d3]
Apomorphine-[13C,d3] is a labelled analogue of Apomorphine which has been used as a dopamine (D1 and D2) receptor agonist, emetic and an antiparkinsonian. Synonyms: (9R)-10-(13C,D3)methyl-10-azatetracyclo[7.7.1.0]heptadeca-1(17),2,4,6,13,15-hexaene-3,4-diol; CS-P-07122; Apomorphine-13C-d3. Grades: > 98%. Molecular formula: C16[13C]H14D3NO2. Mole weight: 271.33.
Apomorphine hydrochloride EP impurity C
Apomorphine hydrochloride EP impurity C. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C34H34N2O4. Mole Weight: 534.66. Catalog: APB10171.
Apomorphine Sulfate-[d5]
Apomorphine Sulfate-[d5] is an isotope compound of Apomorphine Sulfate, a derivative of Apomorphine. Synonyms: (R)-11-hydroxy-1,2,3,6,8,9-D5-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl hydrogen sulfate; [(9R)-3-hydroxy-10-methyl(5, 6, 14, 15, 16-D5)-10-azatetracyclo[7.7.1.0, 7.0, 7]heptadeca-1(17), 2, 4, 6, 13, 15-hexaen-4-yl]oxidanesulfonic acid. Grades: > 98%. Molecular formula: C17H17NO5S. Mole weight: 352.42.
10-O-Benzyl (R)-Apomorphine
10-O-Benzyl (R)-Apomorphine is a benzyl derivative of (R)-Apomorphine (A727500); a dopamine (D1 and D2) receptor agonist, emetic, and antiparkinsonian. Group: Biochemicals. Grades: Highly Purified. CAS No. 701899-34-5. Pack Sizes: 25mg, 250mg. Molecular Formula: C24H23NO2, Molecular Weight: 357.44. US Biological Life Sciences.
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10-O-Benzyl (R)-Apomorphine-d5
10-O-Benzyl (R)-Apomorphine-d5 is the isotope labelled analog of 10-O-Benzyl (R)-Apomorphine (B230300); a benzyl derivative of (R)-Apomorphine (A727500) which is a dopamine (D1 and D2) receptor agonist, emetic, and antiparkinsonian. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C24H18D5NO2, Molecular Weight: 362.48. US Biological Life Sciences.
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Mixture of (R)-Apomorphine-11-sulfate Potassium Salt-d5 + (R)-Apomorphine-10-sulfate. (d4-Major) (90%)
(R)-Apomorphine-11-sulfate Potassium Salt-d5 is the isotope labelled analog of (R)-Apomorphine-11-sulfate Potassium Salt (A727520); a derivative of (R)-Apomorphine (A727500) which is a dopamine (D1 and D2) receptor agonist, emetic, and antiparkinsonian. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C17H11D5KNO5S. US Biological Life Sciences.
Labelled Apomorphine (A727500). Dopamine (D1 and D2) receptor agonist. Emetic. Antiparkinsonian. Group: Biochemicals. Alternative Names: (R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-1,2,3,8,9-d5-10,11-diol-d5 Hydrochloride. Grades: Highly Purified. CAS No. 76787-63-8. Pack Sizes: 1mg. US Biological Life Sciences.
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(R)-Apomorphine Hydrobromide
(R)-Apomorphine Hydrobromide is an impurity in the synthesis of (S)-Apomorphine is an isomer of (R)?-?(-?)?-?Apomorphine (A727495),which is a dopamine (D1 and D2) receptor agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 57072-41-0. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C17H17NO2; HBr. US Biological Life Sciences.
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(R)-(-)-Apomorphine hydrochloride
(R)-(-)-Apomorphine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 314-19-2. Pack Sizes: 50mg. US Biological Life Sciences.
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(R)-Apomorphine hydrochloride
(R)-Apomorphine hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 314-19-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
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(R)-Apomorphine Hydrochloride Hemihydrate
Dopamine (D1 and D2) receptor agonist. Emetic. Antiparkinsonian. Group: Biochemicals. Alternative Names: (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol Hydrochloride Hemihydrate; 6a β-Aporphine-10,11-diol Hydrochloride Hemihydrate; (-)-10,11-Dihydroxy-aporphine Hydrochloride Hemihydrate; Apokyn Hemihydrate; Apomorphin Hemihydrate; Apomorphine Hemihydrate; Ixense Hemihydrate; l-Apomorphine Hemihydrate. Grades: Highly Purified. CAS No. 41372-20-7. Pack Sizes: 25mg. US Biological Life Sciences.
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(S)-Apomorphine hydrochloride
(S)-Apomorphine hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 41035-30-7. Pack Sizes: 25mg, 50mg. Molecular Formula: C17H17NO2·HCl. US Biological Life Sciences.
2,2-Dimethyl-propanoic Acid (6aR)-5,6,6a,7-Tetrahydro-10-hydroxy-6-methyl-4H-dibenzo[de,g]quinolin-11-yl Ester is an intermediate in the synthesis of (R)-Apomorphine-10-sulfate (A727515). Group: Biochemicals. Grades: Highly Purified. CAS No. 1350191-90-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H25NO3, Molecular Weight: 351.44. US Biological Life Sciences.
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2-Bromo-LSD
2-Bromo-LSD (BOL-148; Bromolysergide) is a Dopamine Receptor antagonist that directly affects dopamine neurons in the substantia nigra neostriatum. 2-Bromo-LSD increases the hydroxylation of tyrosine in striatum and antagonizes the decrease of Apomorphine-induced DOPA accumulation. 2-Bromo-LSD also blocks the 5-HT Receptor mediated DOPA formation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BOL-148; Bromolysergide. CAS No. 478-84-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121675.
Boldine
Boldine is an apomorphine isoquinoline alkaloid extracted from the root of the pheasant pepper ( Litsea cubeba ). Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK , AKT and GSK-3&beta. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 476-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N6973.
L-741,626
L-741,626 is a selective and potent D2 dopamine receptor antagonist. It is centrally active following systemic administration in vivo. It inhibits quinpirole-stimulated mitogenesis transfected with human D2 and D3 receptors in a functional assay. It reversibly blocks D2-mediated currents in Xenopus oocytes by G protein-gated inwardly rectifying K+ (GIRK) channels. It inhibits the conditioned avoidance response (CAR) in rats and apomorphine-induced climbing behavior in mice. It evokes a catalepsy response and blocks gnawing induced by methylphenidate in rat models of potential extrapyramidal activity. Uses: Dopamine antagonists. Synonyms: L-741,626; L741,626; L 741,626; 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol; 3-[[4-(4-Chlorophenyl)-4-hydroxypiperidin-l-yl]methyl-1H-indole; 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidin-4-ol; (±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole. Grades: ≥98% by HPLC. CAS No. 81226-60-0. Molecular formula: C20H21ClN2O. Mole weight: 340.85.
Mardepodect free base
Mardepodect, also known as PF-2545920, is a phosphodiesterase inhibitor selective for the PDE10A subtype, which is potentially useful for the treatment of schizophrenia. Phosphodiesterase 10A (PDE10A) is highly expressed in striatal medium spiny neurons of both the direct and indirect output pathways. PDE10A inhibitors have shown behavioral effects in rodent models that predict antipsychotic efficacy. PF-2545920 is active in a range of antipsychotic models, antagonizing apomorphine-induced climbing in mice, inhibiting conditioned avoidance responding in both rats and mice, and blocking N-methyl-D-aspartate antagonist-induced deficits in prepulse inhibition of acoustic startle response in rats, while improving baseline sensory gating in mice. Group: Inhibitors. Alternative Names: PF-2545920; PF 2545920; PF2545920; MP-10; MP10; MP 10, Mardepodect. CAS No. 898562-94-2. Molecular formula: C25H20N4O. Mole weight: 392. Appearance: Solid powder. Purity: >98%. IUPACName: 2-(4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxymethyl)quinoline. Canonical SMILES: CN1N=C (C2=CC=C (OCC3=NC4=CC=CC=C4C=C3)C=C2)C (C5=CC=NC=C5)=C1. Catalog: ACM898562942.
OPC 4392 hydrochloride
OPC 4392 hydrochloride is an agonist for presynaptic dopamine receptor and an antagonist for postsynaptic D2 receptor. OPC 4392 reverses the Reserpine (HY-N0480)-induced dopamine accumulation, inhibits Apomorphine (HY-12723)-induced stereotypic and climbing behaviors in mouse models [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1329509-60-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-106781A.
Pseurotin D
Isomeric to pseurotin A. Anticancer and antiparasitic compound. Apomorphine antagonist. Neuroleptic agent. Inhibitor of IgE production. Group: Biochemicals. Grades: Highly Purified. CAS No. 77409-68-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??NO?. US Biological Life Sciences.
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