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Product
APY29 ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
APY29 Allosteric modulator of IRE1&alpha. Inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α ribonuclease activity. Synonyms: APY29; APY-29; APY 29; N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine. Grades: >98%. CAS No. 1216665-49-4. Molecular formula: C17H16N8. Mole weight: 332.36. BOC Sciences
APY29 APY29, an ATP-competitive inhibitor, is an allosteric modulator of IRE1? which inhibits IRE1? autophosphorylation by binding to the ATP-binding pocket with IC50 of 280 nM. APY29 acts as a ligand that allosterically activates IRE1? adjacent RNase domain[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216665-49-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17537. MedChemExpress MCE

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