Atpase Suppliers USA
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Product | Description | |
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Cytoplasmic Dynein Inhibitor, Ciliobrevin D (2- (7-chloro-4-oxo-3, 4-dihydroquinazolin-2 (1H)-ylidene)-3- (2, 4-dichlorophenyl)-3-oxopropanenitrile) (AAA+ ATPase Motor Cytoplasmic Dynein Inhibitor) Quick inquiry Where to buy Suppliers range | A cell-permeable benzoyl dihydroquinazolinone derivative that acts as a reversible and specific blocker of AAA+ ATPase motor cytoplasmic dynein and disrupts spindle pole focusing, cold-stable microtubule formation, kinetochore-microtubule attachment, and melanosome aggregation in a dose-dependent manner (~10-40uM). Shown to perturb protein trafficking within the primary cilia and cause a significant increase in intraflagellar transport protein 88 (IFT88) levels at the distal tip of primary cilia. Reported to disrupt primary cilium-dependent Gli regulation and block Hedgehog signaling. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
p97 ATPase Activity Inhibitor, DBeQ Quick inquiry Where to buy Suppliers range | The p97 ATPase Activity Inhibitor, DBeQ controls the biological activity of p97 ATPase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 10MG. Mole weight: 340.42. Catalog: IAR42410914. Assay: ≥95% (HPLC). | |
1-(4-(2-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide Quick inquiry Where to buy Suppliers range | 1-(4-(2-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. It is also used in the preparation of guanidinothiazole derivatives as Maillard reaction inhibitors and antioxidants. Group: Biochemicals. Grades: Highly Purified. CAS No. 123310-81-6. Pack Sizes: 500mg, 1g. Molecular Formula: C11H12N4OS; HBr, Molecular Weight: 248.31. US Biological Life Sciences. | Worldwide |
1-(4-(3-Chlorophenyl)thiazol-2-yl)guanidine Hydrobromide Quick inquiry Where to buy Suppliers range | 1-(4-(3-Chlorophenyl)thiazol-2-yl)guanidine Hydrobromide is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. Also used in the preparation of substituted (thiazolylamino) tetra hydropyridopyrimidine derivatives useful as platelet aggregation inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 123310-66-7. Pack Sizes: 500mg, 1g. Molecular Formula: C10H9ClN4S; HBr, Molecular Weight: 252.728091. US Biological Life Sciences. | Worldwide |
1-(4-(3-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide Quick inquiry Where to buy Suppliers range | 1-(4-(3-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide shows antiulcer activity. Also used in the preparation of other antiulcer agents such as 4-Substituted 2-guanidinothiazoles which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C11H12N4OS; HBr, Molecular Weight: 248.31. US Biological Life Sciences. | Worldwide |
1-[4-(4-Ethoxyphenyl)thiazol-2-yl]-guanidine Hydrobromide Quick inquiry Where to buy Suppliers range | 1-[4-(4-Ethoxyphenyl)thiazol-2-yl]-guanidine Hydrobromide is related to 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide (M226305), which is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is also used in the preparation of thiazole compounds as myosin light chain phosphatase inhibitors for prostate cancer treatment. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg. Molecular Formula: C12H14N4OS; HBr, Molecular Weight: 262.34. US Biological Life Sciences. | Worldwide |
1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide Quick inquiry Where to buy Suppliers range | 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is also used in the preparation of thiazole compounds as myosin light chain phosphatase inhibitors for prostate cancer treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 96996-05-3. Pack Sizes: 500mg, 1g. Molecular Formula: C11H12N4OS; HBr, Molecular Weight: 248.31. US Biological Life Sciences. | Worldwide |
1,4-Dihydro-1-(5-methoxy-1H-benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-pyridinecarboxylic Acid Ammonium Salt Quick inquiry Where to buy Suppliers range | 1,4-Dihydro-1-(5-methoxy-1H-benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-pyridinecarboxylic Acid Ammonium Salt is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: OMP-A Ammonium Salt. CAS No. 2227107-89-1. Molecular formula: C16H18N4O4. Mole weight: 330.34. | |
17-AAG Quick inquiry Where to buy Suppliers range | Potent, less toxic analog of geldanamycin. Inhibits the essential ATPase activity of HSP90. Telomerase activity inhibitor. Apoptosis inducer and antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 75747-14-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
17(S)-HETE Quick inquiry Where to buy Suppliers range | 17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney.17(S)-HETE inhibits proximal tubule ATPase activity by as much as 70% at a concentration of 2 μM. Synonyms: 17-hydroxyicosa-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 183509-25-3. Molecular formula: C20H32O3. Mole weight: 320.5. | |
1-Hexanol Quick inquiry Where to buy Suppliers range | 1-Hexanol was examined as a perturbing agent on actomyosin ATPase and and was found to modulate the function of actomyosin motor via intermediate-specific structural perturbation. Group: Biochemicals. Alternative Names: Hexyl Alcohol (8CI); 1-Hexyl Alcohol; 1-Hydroxyhexane; Amylcarbinol; Caproyl Alcohol; Epal 6; Hexanol; NSC 9254; Pentylcarbinol; n-Hexan-1-ol; n-Hexanol; n-Hexyl Alcohol. Grades: Highly Purified. CAS No. 111-27-3. Pack Sizes: 10ml. US Biological Life Sciences. | Worldwide |
20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid Quick inquiry Where to buy Suppliers range | 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid is a potent vasoconstrictor produced in vascular smooth muscle cells. Its EC50 value is < 10 nM. It is a cytochrome P450 metabolite. It induces diuresis by inhibiting Na+-K+-ATPase in proximal tubules and Na+/K+/Cl+ cotransporter in the thick ascending limb of Henle's loop in kidney. It is involved in the regulation of sodium, potassium, and chloride transport in the renal tubules. It is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction in rat cerebral microvessels. It is excreted mainly as the glucuronide conjugate. It can be further metabolized by cyclooxygenase to 20-hydroxy PGG2 and 20-hydroxy PGH2. It regulates blood pressure in a complex way. It sensitizes smooth muscle cells to the constrictor stimuli and promotes the proliferation of endothelial cells. It has the ability to induce proinflammatory changes. It blocked the 70 pS K+ channel localized in the apical membrane in TALH cells. It was found to be a potent vasoconstrictor through activating the kinase pathways that contribute to the vascular tone regulation including MAPK, PKC, rho kinase and src-type tyrosine kinase. It may similarly regulate blood pressure and contribute to the development of stroke and heart attacks. Synonyms: 20-Hydroxyeicosatetraeonic acid; 20 Hydroxyeicosatetraeonic acid; 20Hydroxyeicosatetraeonic acid; 20HETE; 20 HETE; 20-HETE;(5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid;20-Hydroxyeicosatetraenoic acid;20-hydroxy-5,8,11,14-eicosatetraenoic acid. Grades: >98%. CAS No. 79551-86-3. Molecular formula: C20H32O3. Mole weight: 320.47. | |
2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-5,7-dihydroxy-3-(phenylmethoxy)-4H-1-benzopyran-4-one Quick inquiry Where to buy Suppliers range | 2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-5,7-dihydroxy-3-(phenylmethoxy)-4H-1-benzopyran-4-one is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. Group: Biochemicals. Grades: Highly Purified. CAS No. 498548-17-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C35H24O7. US Biological Life Sciences. | Worldwide |
2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-5-hydroxy-3,7-bis(phenylmethoxy)-4H-1-benzopyran-4-one Quick inquiry Where to buy Suppliers range | 2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-5-hydroxy-3,7-bis(phenylmethoxy)-4H-1-benzopyran-4-one is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C42H30O7. US Biological Life Sciences. | Worldwide |
2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-5-hydroxy-3-phenylmethoxy-4H-1-benzopyran-4-one 7-O- β-D-Glucuronide Quick inquiry Where to buy Suppliers range | 2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-5-hydroxy-3-phenylmethoxy-4H-1-benzopyran-4-one 7-O- β-D-Glucuronide is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C41H32O13. US Biological Life Sciences. | Worldwide |
2- (2-Isopropyl-5-methylphenoxy) ethanamine Quick inquiry Where to buy Suppliers range | 2- (2-Isopropyl-5-methylphenoxy) ethanamine has been used as a reactant in the discovery of novel sacro/endoplasmic reticulum calcium ATPase (SERCA) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 26583-34-6. Pack Sizes: 1g, 10g. Molecular Formula: C12H19NO, Molecular Weight: 193.29. US Biological Life Sciences. | Worldwide |
2,3-Butanedione-2-monoxime Quick inquiry Where to buy Suppliers range | 2,3-Butanedione-2-monoxime (BDM) is a non-selective, reversible myosin ATPase inhibitor with phosphatase-like properties. It is non-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Uses: Cholinesterase reactivators. Synonyms: BDM; Diacetyl Monoxime; NSC 660; NSC 116103; Biacetyl monooxime. Grades: ≥95%. CAS No. 57-71-6. Molecular formula: C4H7NO2. Mole weight: 101.1. | |
2,3-Butanedione 2-Monoxime Quick inquiry Where to buy Suppliers range | 2,3-Butanedione 2-Monoxime is a reversible inhibitor of myosin ATPase. Group: Biochemicals. Grades: Highly Purified. CAS No. 57-71-6. Pack Sizes: 25g, 50g. Molecular Formula: C4H7NO2, Molecular Weight: 101.1. US Biological Life Sciences. | Worldwide |
2'/3'-(N-Methylanthraniloyl)-adenosine-5'-triphosphate triethylammonium salt Quick inquiry Where to buy Suppliers range | The 2'/3'-(N-Methylanthraniloyl)-adenosine-5'-triphosphate triethylammonium salt, an essential compound utilized in the biomedical sector, exhibits its significance as a robust fluorescent probe for comprehensive investigations into diverse biological phenomena. Researchers predominantly employ this prolific product to delve into enzymatic reactions, nucleotide binding, and ATPase activity. Furthermore, it facilitates the exploration of drug influences, receptor-ligand interplays, and signal transduction pathways associated with manifold maladies. Synonyms: (2R, 3R, 4R, 5R) -2- (6-Amino-9H-purin-9-yl) -4-hydroxy-5- ( ( (hydroxy ( (hydroxy (phosphonooxy) phosphoryl) oxy) phosphoryl) oxy) methyl) tetrahydrofuran-3-yl 4-(methylamino)benzoate; 175737-77-6. CAS No. 175737-77-6. Molecular formula: C18H23N6O14P3·xC6H16N. Mole weight: 640.33 (free acid). | |
2-Aminoadenosine-5'-Triphosphate Quick inquiry Where to buy Suppliers range | 2-Aminoadenosine-5'-Triphosphate, a versatile compound, finds extensive applications in enzymology and biotechnology as a substrate for kinases, ATPases, and nucleotide pyrophosphatases. Additionally, it is noteworthy for its ability to stimulate bone resorption activity in separated osteoclasts, therefore facilitating the study of bone metabolism and related diseases like osteoporosis and osteopenia. Synonyms: 2-Amino-ATP; 2,6-Diaminopurine-ribose-5'-Triphosphate; DAP-rTP. Grades: ≥90% by AX-HPLC. CAS No. 18549-34-3. Molecular formula: C10H17N6O13P3. Mole weight: 522.20. | |
2'-Chloro-N6-(4-trifluoromethyl)benzyladenosine Quick inquiry Where to buy Suppliers range | 2'-Chloro-N6-(4-trifluoromethyl)benzyladenosine, a small molecule ATP analog, exhibits multifaceted potential for biomedical research and therapeutic development. Its effects are formidable as a potent inhibitor of numerous ATP-dependent enzymes, including protein kinases and ATPases. Aside from its use in studying complex biochemical mechanisms, it has promise for clinical application in combatting diseases such as certain cancers that involve ATP-dependent processes. Synonyms: Adenosine, 2-chloro-N-[[4-(trifluoromethyl)phenyl]methyl]-; (2R, 3R, 4S, 5R) -2-[2-chloro-6-[[4- (trifluoromethyl) phenyl]methylamino]purin-9-yl]-5- (hydroxymethyl) oxolane-3, 4-diol. Grades: ≥95%. CAS No. 722515-03-9. Molecular formula: C18H17ClF3N5O4. Mole weight: 459.81. | |
2-Naphthyl phosphate calcium salt hydrate Quick inquiry Where to buy Suppliers range | 2-Naphthyl Phosphate Calcium Salt Hydrate inhibits photophosphorylation competitively with inorganic phosphate on chloroplast-light triggered ATPase. Synonyms: calcium;naphthalen-2-yl hydrogen phosphate;hydrate. CAS No. 305808-24-6. Molecular formula: C20H18CaO9P2. Mole weight: 262.21 (anhydrous basis). | |
2-Naphthyl Phosphate Calcium Salt Hydrate Quick inquiry Where to buy Suppliers range | 2-Naphthyl Phosphate Calcium Salt Hydrate inhibits photophosphorylation competitively with inorganic phosphate on chloroplast-light triggered ATPase. Group: Biochemicals. Grades: Highly Purified. CAS No. 305808-24-6. Pack Sizes: 1g, 5g. Molecular Formula: C10H9O4P; (Ca); X(H2O), Molecular Weight: 224.1540081802. US Biological Life Sciences. | Worldwide |
3-[(2-Methyl-2-propen-1-yl)thio]-5H-1,2,4-triazino[5,6-b]indole Quick inquiry Where to buy Suppliers range | 3-[(2-Methyl-2-propen-1-yl)thio]-5H-1,2,4-triazino[5,6-b]indole is a triazinoindole derivative that inhibits eukaryotic ribosome biogenesis (1). It is also an ATPase inhibitor (1). Group: Biochemicals. Grades: Highly Purified. CAS No. 328023-11-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C13H12N4S, Molecular Weight: 256.33. US Biological Life Sciences. | Worldwide |
3-(4-Aminophenyl)-1,3-oxazolidin-2-one Quick inquiry Where to buy Suppliers range | 3-(4-Aminophenyl)-1,3-oxazolidin-2-one is a reactant used in the preparation of N-phenyl-4,5-dibromopyrrolamides and N-phenylindolamides which can act as ATPase inhibitors of DNA gyrase. Group: Biochemicals. Grades: Highly Purified. CAS No. 22036-26-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H10N2O2, Molecular Weight: 178.19. US Biological Life Sciences. | Worldwide |
3β-Amino-3-Deoxydigoxigenin Hemisuccinamide Succinimidyl Ester Quick inquiry Where to buy Suppliers range | 3β-Amino-3-Deoxydigoxigenin Hemisuccinamide Succinimidyl Ester is an amine-reactive derivative of Digoxigenin. It has been shown to inhibit the Na+/K+ ATPase by binding to the cardiac steroid receptor site. Synonyms: 3β-Amino-3-deoxydigitoxigenin Hemisuccinate N-Succinimidyl Ester; (3β,5β,12β)-3-[[4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-1,4-dioxobutyl]amino]-12,14-dihydroxycard-20(22)-enolide. CAS No. 216299-46-6. Molecular formula: C31H42N2O9. Mole weight: 586.67. | |
4-[[4-Oxo-2-thioxo-3-[3-(trifluoromethyl)benzyl]thiazolidin-5-ylidene]methyl]benzoic Acid Quick inquiry Where to buy Suppliers range | CY-09 is a selective and direct NLRP3 inflammasome inhibitor which directly targeted NLRP3 itself. It directly binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity, resulting in the suppression of NLRP3 inflammasome assembly and activation. Synonyms: 4-[(Z)-[4-oxo-2-sulfanylidene-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid; 4-[(Z)-[4-oxo-2-sulfanylidene-3-[[3-(trifluoromethyl)phenyl]methyl]-1,3-thiazolidin-5-ylidene]methyl]benzoic acid. Grades: ≥ 98 %. CAS No. 1073612-91-5. Molecular formula: C19H12F3NO3S2. Mole weight: 423.43. | |
4,5'-Di(desmethyl) Omeprazole Quick inquiry Where to buy Suppliers range | An impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 4,5'-Di(desmethyl) Omeprazole. Grades: > 95%. Molecular formula: C15H15N3O3S. Mole weight: 317.37. | |
4'-Desmethoxy Omeprazole Quick inquiry Where to buy Suppliers range | 4'-Desmethoxy Omeprazole is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 2-(4-Methoxy-3,5-dimethyl-pyridin-2-ylmethanesulfinyl)-1H-benzoimidazole; 2-[(3,5-Dimethyl-4-methoxy-2-pyridinyl)methylsulfinyl]-1H-benzimidazole; 2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole. Grades: > 95%. CAS No. 73590-60-0. Molecular formula: C16H17N3O2S. Mole weight: 315.39. | |
4-Desmethoxy Omeprazole Sulfide Quick inquiry Where to buy Suppliers range | 4-Desmethoxy Omeprazole Sulfide is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 5-Methoxy-2-[[(3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole; 5-Methoxy-2-[[(3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole. Grades: >95%. CAS No. 704910-89-4. Molecular formula: C16H17N3OS. Mole weight: 299.39. | |
4-Hydroxy Omeprazole Sodium Salt Quick inquiry Where to buy Suppliers range | 4-Hydroxy Omeprazole Sodium Salt is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: Esomeprazole Impurity H215/01; Esomeprazole Impurity G. Grades: >95%. CAS No. 1803449-15-1. Molecular formula: C16H15N3Na2O3S. Mole weight: 375.35. | |
4-Nitropyridine N-Oxide Quick inquiry Where to buy Suppliers range | The N-oxide derivative of a nitrated pyridine that has been shown to inhibit Na,K-ATPase activity. 4-Nitropyridine N-Oxide is a quorum sensing inhibitor. Group: Biochemicals. Alternative Names: 4-Nitropyridine 1-Oxide; 4-Nitropyridine Oxide; NSC 130895; NSC 5079; p-Nitropyridine N-Oxide. Grades: Highly Purified. CAS No. 1124-33-0. Pack Sizes: 1g, 10g. US Biological Life Sciences. | Worldwide |
5-Hydroxy Omeprazole Quick inquiry Where to buy Suppliers range | 5-Hydroxy Omeprazole is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 5-Hydroxyomeprazole; 4-Methoxy-6-{[(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl}-5-methyl-3-pyridinemethanol; 5-Methoxy-2-{[(5-hydroxymethyl-4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole; Hydroxyomeprazole. Grades: >95%. CAS No. 92340-57-3. Molecular formula: C17H19N3O4S. Mole weight: 361.42. | |
5-Methoxy-2-(4-Methoxy-3,5-Dimethylpyridin-2-yl)-1H-Benzimidazole Quick inquiry Where to buy Suppliers range | An impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 5-Methoxy-2-(4-Methoxy-3,5-Dimethylpyridin-2-yl)-1H-Benzimidazole. Grades: > 95%. Molecular formula: C16H17N3O2. Mole weight: 283.33. | |
5-O-Desmethyl Omeprazole Quick inquiry Where to buy Suppliers range | 5-O-Desmethyl Omeprazole is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Uses: A metabolite of omeprazole, an antiulcerative. Synonyms: 1H-Benzimidazol-6-ol, 2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-; 1H-Benzimidazol-5-ol, 2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-; 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-6-ol; 5-O-Desmethylomeprazole. Grades: >90%. CAS No. 151602-49-2. Molecular formula: C16H17N3O3S. Mole weight: 331.39. | |
8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate - 5/6-TAMRA Quick inquiry Where to buy Suppliers range | 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate - 5/6-TAMRA, commonly employed in biomedical research, is an illuminating fluorescence-labeled analogue of adenosine triphosphate (ATP). With it, ATPase enzyme activity, localization, and functions can be studied. This product has culminated in invaluable contributions to combating grave afflictions such as cancer and neurological disorders. It is further utilized in drug discovery and, through its robust capacity to monitor in vivo ATP levels, allows a window into the cellular milieu. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate, labeled with 5/6-TAMRA, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H49N9O14P2 (free acid). Mole weight: 953.83 (free acid). | |
8-[(6-Amino)hexyl]-amino-ATP - ATTO-532 Quick inquiry Where to buy Suppliers range | 8-[(6-Amino)hexyl]-amino-ATP - ATTO-532, a fluorescent derivative of ATP, is widely employed to explore central ATP-dependent processes in vibrant cellular systems. Its capacity to link to critical ATP-binding proteins like kinases and ATPases allows adventurers and mavens to detect and visualize these enzymes in their natural habitats, the live cells. Besides, ATTO-532 dye, an integral component, produces a stable and luminous signal suitable for all imaging applications. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C45H59N10O22P3S2 (free acid). Mole weight: 1249.06 (free acid). | |
ACBI1 Quick inquiry Where to buy Suppliers range | ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis. Synonyms: ACBI 1; ACBI-1; (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide. CAS No. 2375564-55-7. Molecular formula: C49H58FN9O7S. Mole weight: 936.12. | |
Acetyldigitoxin Quick inquiry Where to buy Suppliers range | Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes. Synonyms: Desglucolanatoside A. Grades: ≥95%. CAS No. 1111-39-3. Molecular formula: C43H66O14. Mole weight: 807. | |
Adenosine 5'-diphosphate monopotassium salt Quick inquiry Where to buy Suppliers range | Adenosine 5'-diphosphate (ADP) is an adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5' position. It is produced by dephosphorylation of adenosine 5'-triphosphate by ATPases and can be converted back to ATP by ATP synthases. Synonyms: Adenosine 5'-(trihydrogen diphosphate), monopotassium salt; Adenosine 5'-Diphosphate Potassium Salt; 5'-ADP monopotassium salt; ADP monopotassium salt. Grades: ≥95%. CAS No. 70285-70-0. Molecular formula: C10H14N5O10P2·K. Mole weight: 465.29. | |
Adenosine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | Adenosine-5'-O-(1-Thiotriphosphate) - this nucleotide analog, frequently used in biochemical research to investigate ATP-utilizing enzymes, shows promise in treating cancer and neurological maladies by inhibiting particular biological enzyme activity. Additionally, it can assess the effect of drugs on the ATPase activity of proteins, making it a valuable tool in pharmacology. Synonyms: Alpha Thiol ATP; 1-Thio-ATP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H16N5O12P3S. Mole weight: 523.25. | |
Aldometanib Quick inquiry Where to buy Suppliers range | Aldometanib is an active aldolase inhibitor. It prevents FBP from binding to v-ATPase-associated aldolase and activates lysosomal AMPK. Aldometanib can be used for the research of metabolic homeostasis. Grades: >98.0%. CAS No. 2904601-67-6. Molecular formula: C27H43Cl2IN2. Mole weight: 593.46. | |
Anisodamine Quick inquiry Where to buy Suppliers range | Anisodamine, an anticholinergic drug, has antishock effect, which is intimately linked to alpha7nAChR-dependent anti-inflammatory pathway. Anisodamine demonstrates a direct cardiac depressive action at the myocyte level, which may be related to, at least in part, NO production and cholinoceptor antagonism, it causes the changes of structure and function in the transmembrane domain of the Ca(2+)-ATPase from sarcoplasmic reticulum. Anisodamine, a vasoactive drug, can abate endogenous endotoxaemia subsequent to splanchnic vasoconstriction due to hypovolaemia, it alleviates inflammatory damage by significantly reducing the expressions of VEGF and ICAM-1, and shows significant protective effects in an animal model of infusion phlebitis. Anisodamine also inhibits shiga toxin type 2-mediated tumor necrosis factor-alpha production in vitro and in vivo. Group: Biochemicals. Grades: Plant Grade. CAS No. 55869-99-3. Pack Sizes: 100mg. Molecular Formula: C17H23NO4, Molecular Weight: 305.374. US Biological Life Sciences. | Worldwide |
Apoptolidin Quick inquiry Where to buy Suppliers range | Apoptolidin, originally isolated from a Nocardiopsis sp., induces apoptotic cell death in rat glial cells transformed with the adenovirus E1A oncogene at an IC50 = 11 ng/ml. It is among the most selective cytotoxic agents tested by the NCI in human cancer cell lines. Although the apoptotic activity of apoptolidin correlates with F0F1-ATPase inhibition, recent evidence suggests the existence of a secondary biological target or more complex mode of action. Group: Biochemicals. Grades: Highly Purified. CAS No. 194874-06-1. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
Apoptozole Quick inquiry Where to buy Suppliers range | Apoptozole, also known as Apoptosis Activator VII, is an apoptosis-inducing small molecule that inhibits the ATPase activity of heat shock cognate 70 (Hsc70) and Hsp70 (Kd = 210 and 140 nM, respectively). Apoptozole dose-dependently induces apoptosis in cancer cells (IC50 = 5-7 μM). Synonyms: 4-((2-(3,5-bis(trifluoromethyl)phenyl)-4,5-bis(4-methoxyphenyl)-1H-imidazol-1-yl)methyl)benzamide; Apoptozole; Apoptosis Activator VII. CAS No. 1054543-47-3. Molecular formula: C33H25F6N3O3. Mole weight: 625.57. | |
ARL 67156 Quick inquiry Where to buy Suppliers range | ARL 67156 is an ecto-ATPase inhibitor/ATP analog. Synonyms: ARL 67157; FPL 67156. CAS No. 160928-38-1. Molecular formula: C15H24Br2N5O12P3. Mole weight: 719.11. | |
ARL 67156 trisodium salt Quick inquiry Where to buy Suppliers range | The sodium salt form of ARL 67156, which has been found to be an ecto-ATPase inhibitor. Synonyms: ARL 67156; ARL-67156; ARL67156; 6-N,N-Diethyl-D-β,γ-dibromomethyleneATP trisodium salt. Grades: ≥98% by HPLC. CAS No. 1021868-83-6. Molecular formula: C15H21Br2N5O12P3.3Na. Mole weight: 785.06. | |
ARQ-621 Quick inquiry Where to buy Suppliers range | ARQ-621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Over-expression of Eg5 causes genomic instability and tumor formation in mice. Preclinical data shows anti-tumor activity of ARQ 621 across a wide range of cell lines from human solid and hematological malignancies. Synonyms: NSC-771644; N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluorobenzamide; (R)-N-(3-Aminopropyl)-3-chloro-N-(1-(7-chloro-4-oxo-3-(phenylamino)-3,4-dihydroquinazolin-2-yl)but-3-yn-1-yl)-2-fluorobenzamide; Benzamide, N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluoro-. Grades: ≥95%. CAS No. 1095253-39-6. Molecular formula: C28H24Cl2FN5O2. Mole weight: 552.43. | |
ATP-acetyl-desthiobiotin Quick inquiry Where to buy Suppliers range | ATP-acetyl-desthiobiotin is a paramount recompound in the realm of biomedical researchdue to its remarkable potential in scrutinizing intricate protein functionalities. With its unparalleled proclivity for ATP-dependent enzymes, it serves as an invaluable tool for monitoring and discerning the intricacies of ATPases, aTP-binding proteins and ATP-utilizing enzymes. Synonyms: Desthiobiotin-ATP probe; Desthiobiotin-acyl-ATP. Molecular formula: C20H32N7O15P3. Mole weight: 703.43. | |
AU-15330 Quick inquiry Where to buy Suppliers range | AU-15330 is highly specific and VHL-dependent PROTAC degrader of the SWI/SNF ATPase components (SMARCA2, SMARCA4 and PBRM1). It induces effective inhibition of tumour growth in xenograft models of prostate cancer and acts synergistically with enzalutamide, an AR antagonist. It induces disease remission in castration-resistant prostate cancer (CRPC) models and is nontoxic. Synonyms: AU 15330; AU15330; (2S,4R)-1-((S)-2-(2-(4-(3-Amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide. Grades: ≥95%. CAS No. 2380274-50-8. Molecular formula: C39H49N9O5S. Mole weight: 755.93. | |
Bafilomycin A1 (NSC381866) Quick inquiry Where to buy Suppliers range | Bafilomycin A1 is a member of a potent family of macrocyclic lactones with a broad spectrum of biological activity including activity against bacteria, yeast, fungi, nematodes, insects and antitumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase. Related to: Bafilomycin B1, Bafilomycin C1, Concanamycin A.Source:Streptomyces griseus. Group: Biochemicals. Alternative Names: 21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-hygrolidin Oxacyclohexadecane, hygrolidin deriv.; (-)-Bafilomycin A1; NSC 381866; [7R-[3Z, 5E, 7R*, 8S*, 9S*, 11E, 13E, 15S*, 16R*[1S*, 2R*, 3S*(2R*, 4R*, 5S*, 6R*)]]]-8-Hydroxy-16-[2-hydroxy-1-methyl-3-[tetrahydro-2, 4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3, 15-dimethoxy-5, 7, 9, 11-tetramethyl-oxacyclohexadeca-3, 5, 11, 13-tetraen-2-one. Grades: Highly Purified. CAS No. 88899-55-2. Pack Sizes: 100ug, 1mg. Molecular Formula: C35H58O9, Molecular Weight: 622.8. US Biological Life Sciences. | Worldwide |
Bafilomycin B1 (Setamycin, BRN4640118) Quick inquiry Where to buy Suppliers range | Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 88899-56-3. Pack Sizes: 100ug, 1mg, 5mg. US Biological Life Sciences. | Worldwide |
Bafilomycin C1 Quick inquiry Where to buy Suppliers range | Bafilomycin C1 is a macrolide compound found in Streptomyces and an inhibitor of V-ATPase protein. It has a wide range of activities against bacteria, fungi, insects, and nematodes. It is a potential drug for the treatment of osteoporosis. Synonyms: L-681,110A1. Grades: >95% by HPLC. CAS No. 88979-61-7. Molecular formula: C39H60O12. Mole weight: 720.88. | |
Bafilomycin C1 (Antibiotic L-681,110A1) Quick inquiry Where to buy Suppliers range | Bafilomycin C1 shares the same mode of action and activity as its more accessible A1 analogue Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential antiosteoporotic agent in treating bone lytic diseases.The presence of the fumarate group has provided an ideal ligand for affinity chromatography of V-ATPase. Group: Biochemicals. Alternative Names: Antibiotic L-681,110A1. Grades: Highly Purified. CAS No. 88979-61-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Bafilomycin C1 (L-681,110A1, 2-Demethyl-2-methoxy-24-methyl-hygrolidin) Quick inquiry Where to buy Suppliers range | Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, antifungal, insecticidal and antihelmintic. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 88979-61-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Bafilomycin D (Tubaymycin, Antibiotic 3D5) Quick inquiry Where to buy Suppliers range | Bafilomycin D shares the same mode of action as bafilomycin A1 which has been the analog of choice in cell biology studies of the role of ATPase. Bafilomycin D contains the ring opened side chain and is a much more stable analog of bafilomycin A1. In-house data demonstrate that bafilomycin D is also a much more selective inhibitor of mammalian cells than bafilomycin A which exhibits a broad profile against tumor cells, fungi and nematodes. Limited availability has restricted a more in depth investigation of this metabolite. Group: Biochemicals. Alternative Names: Tubaymycin, Antibiotic 3D5. Grades: Highly Purified. CAS No. 98813-13-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
BAY-850 Quick inquiry Where to buy Suppliers range | BAY-850 is a potent isotype-selective ATPase family AAA domain protein 2 (ATAD2) inhibitor with IC50 of 166 nM and can be used as a probe. Grades: 98%. CAS No. 2099142-76-2. Molecular formula: C38H44ClN5O3. Mole weight: 654.2. | |
Bis-Desmethoxy Omeprazole Sulfide Quick inquiry Where to buy Suppliers range | Bis-Desmethoxy Omeprazole Sulfide is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 2-(((3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole. CAS No. 704910-94-1. Molecular formula: C15H15N3S. Mole weight: 269.40. | |
(+)-Blebbistatin Quick inquiry Where to buy Suppliers range | (+)-Blebbistatin is the inactive enantiomer of Blebbistatin, an inhibitor of myosin II ATPase. (+)-Blebbistatin can be used as a negative control of the active enatiomer (-)-Blebbistatin. Synonyms: (R)-(+)-Blebbistatin; (3aR)-(+)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grades: ≥99% by HPLC. CAS No. 1177356-70-5. Molecular formula: C18H16N2O2. Mole weight: 292.34. | |
(-)-Blebbistatin Quick inquiry Where to buy Suppliers range | (-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Synonyms: (S)-(-)-Blebbistatin; (S)-blebbistatin; (3aS)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Grades: >98%. CAS No. 856925-71-8. Molecular formula: C18H16N2O2. Mole weight: 292.33. | |
(±)-Blebbistatin Quick inquiry Where to buy Suppliers range | (±)-Blebbistatin is a selective inhibitor of myosin II ATPase. It reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Synonyms: Blebbistatin; (±)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grades: ≥98% by HPLC. CAS No. 674289-55-5. Molecular formula: C18H16N2O2. Mole weight: 292.34. | |
BRITE 338733 Quick inquiry Where to buy Suppliers range | BRITE 338733 is a novel ATPase inhibitor. BRITE 338733 inhibits the expression of RecA in bacteria (IC50 = 4.7 μM) for the treatment of bacterial infections. Uses: A novel atpase inhibitor for the treatment of bacterial infections. Synonyms: BCP0008025; BRITE338733; BCP 0008025; BRITE 338733; BCP-0008025; BRITE-338733; 2-(4-(5-ethylfuran-2-yl)-6-(2,2,6,6-tetramethylpiperidin-4-ylamino)pyridin-2-yl)-4-methylphenol;2-(6-(2,2,6,6-tetramethylpiperidin-4-ylamino)-4-(5-ethylfuran-2-yl)pyridin-2-yl)-4-methylphenol. Grades: ≥98%. CAS No. 503105-88-2. Molecular formula: C27H35O2N3. Mole weight: 433.59. | |
BTB06584 Quick inquiry Where to buy Suppliers range | BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. It may represent a valuable tool to selectively inhibit mitochondrial F1 Fo-ATPase activity without compromising ATP synthesis and to limit ischaemia-induced injury caused by reversal of the mitochondrial F1 Fo-ATPsynthase. Synonyms: BTB06584; BTB-06584; BTB 06584. Grades: >98%. CAS No. 219793-45-0. Molecular formula: C19H12ClNO6S. Mole weight: 417.82. | |
BTB-1 Quick inquiry Where to buy Suppliers range | BTB-1 is a novel small molecule inhibitor of the mitotic motor protein Kif18A, which was identified by Catarinella et al. during a highthroughput screen against Kif18A's MT-stimulated ATPase activity, with an IC50 of 1.7-1.9 M. It is selective within the kinesin subgroup of Kif4, Eg5, MKLP-1, MKLP-2, MPP1, CENP-E and MCAK, and during in vitro motility assays Kif18A's MT gliding ability was blocked by the addition of BTB-1 in a reversible manner. BTB-1 was found to be ATP competitive and MT uncompetitive, only inhibiting the ATPase activity of the MT-bound motor protein. BTB-1 could serve as a valuable tool in disentangling the nature of Kif18A's double functionality within mitosis and assessing for potential therapeutic utilities. Synonyms: BTB 1; BTB1; 4-Chloro-2-nitro-1-(phenylsulfonyl)benzene; 4-Chloro-2-nitrodiphenyl sulfone; NSC 156750. CAS No. 86030-08-2. Molecular formula: C12H8ClNO4S. Mole weight: 297.71. | |
BTS Quick inquiry Where to buy Suppliers range | A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin's interaction with F-actin. Does not affect platelet myosin II. Synonyms: BTS; BnNHTs; N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine. Grades: >98%. CAS No. 1576-37-0. Molecular formula: C14H15NO2S. Mole weight: 261.34. | |
BzATP triethylammonium salt Quick inquiry Where to buy Suppliers range | The P2X purinergic receptors are ligand-gated ion channels that are activated by extracellular ATP. BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5-10 fold greater potency than ATP with EC50 of 0.7 μM. It also exhibits partial agonist activity at P2X1 and P2Y1 receptors. BzATP can also be used as a photoaffinity probe to study adenine nucleotide binding to ATPases. Synonyms: BzATP; Benzoylbenzoic adenosine 5'-triphosphate. Grades: ≥95%. CAS No. 112898-15-4. Molecular formula: C30H39N6O15P3. Mole weight: 816.6. | |
BzATP triethylammonium salt Quick inquiry Where to buy Suppliers range | Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist. Prototypic P2X7 receptor agonist (EC50 values are 3.6, 7 and 285 uM for rat, human and mouse receptors respectively). Exhibits 5 - 10 fold greater potency than ATP. Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase. Group: Biochemicals. Grades: Highly Purified. CAS No. 112898-15-4. Pack Sizes: 1mg. Molecular Formula: C24H24N5O15P3. C18H45N3, Molecular Weight: 1018.97. US Biological Life Sciences. | Worldwide |
BzATP Triethylammonium Salt (2 (3) -O- (4-Benzoylbenzoyl) adenosine-5-triphosphate tri(triethylammonium) Salt, P2X7 Purinergic Receptor Agonist, BZATP, 2 ,3 -O-(4-benzoylbenzoyl)ATP, P2X Purinergic Receptor Agonist, BZATP) Quick inquiry Where to buy Suppliers range | A prototypic P2X7 purinergic receptor agonist that exhibits about 3-fold higher agonistic potency for induction of nucleotide channels than ATP (EC50 = 15uM vs 50uM). Serves as a photo-affinity analog of ATP. Its agonistic activity is significantly reduced in the presence of serum albumin. Can serve as a substrate analog for submitochondrial particle ATPase activity (Km = 940uM). Induces a dose-dependent decrease in wild-type murine neural progenitor cell viability and an increase in caspase-3 activity. These effects are not observed in P2X7-/- mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 112898-15-4. Pack Sizes: 1mg. Molecular Formula: C??H??N?O??P? 3C?H??N. US Biological Life Sciences. | Worldwide |
Caloxin 2A1 Quick inquiry Where to buy Suppliers range | Caloxin 2A1 is a selective extracellular peptide inhibitor of the plasma membrane Ca2+-ATPase (PMCA). It has no effect on basic Mg2+-ATPase or Na+-K+-ATPase. Synonyms: H-Val-Ser-Asn-Ser-Asn-Trp-Pro-Ser-Phe-Pro-Ser-Ser-Gly-Gly-Gly-NH2; L-valyl-L-seryl-L-asparagyl-L-seryl-L-asparagyl-L-tryptophyl-L-prolyl-L-seryl-L-phenylalanyl-L-prolyl-L-seryl-L-seryl-glycyl-glycyl-glycinamide; Glycinamide, L-valyl-L-seryl-L-asparaginyl-L-seryl-L-asparaginyl-L-tryptophyl-L-prolyl-L-seryl-L-phenylalanyl-L-prolyl-L-seryl-L-serylglycylglycyl-. Grades: ≥95%. CAS No. 350670-85-8. Molecular formula: C64H91N19O22. Mole weight: 1478.54. | |
CAY10719 Quick inquiry Where to buy Suppliers range | ABCG2 is a constitutively expressed ATP-binding cassette (ABC) transporter that protects many tissues against xenobiotic molecules. CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 with IC50 of 0.23 μM. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and inhibit ATPase activity. Synonyms: CAY 10719; CAY-10719. Grades: ≥98%. CAS No. 1942919-63-2. Molecular formula: C25H20Cl2N2O2. Mole weight: 451.3. |