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| Product | Description | |
|---|---|---|
| AZ304 | AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC 50 s of 79 nM, 38 nM and 68 nM, respectively. AZ304 also has significant effect on other kinases, such as p38 ( IC 50 , 6 nM), CSF1R ( IC 50 , 35 nM). Anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 942507-42-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117273. |  |
| AZ304 | AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC50s of 79 nM, 38 nM and 68 nM, respectively. AZ304 also has significant effect on other kinases, such as p38 with IC50 of 6 nM, CSF1R with IC50 of 35 nM. It shows antitumor activity. Synonyms: AZ-304; AZ 304. Grades: ≥98%. CAS No. 942507-42-8. Molecular formula: C27H25N5O2. Mole weight: 451.52. |  |
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