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| Product | Description | |
|---|---|---|
| AZD3229 | AZD3229 is a potent pan- KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. AZD3229 inhibits c-KIT with an IC 50 value of 223.3 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2248003-60-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112802. |  |
| AZD3229 | AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It selectively inhibits growth of c-Kit mutant with GI50s of 1971 nM and PDGFR mutant with GI50s of 122 nM). AZD3229 demonstrates excellent cross-species pharmacokinetics, shows strong pharmacodynamic inhibition of target, and is active in several in vivo models of GIST. Synonyms: AZD-3229; AZD 3229; N-{4-[(6,7-dimethoxyquinazolin-4-yl)oxy]phenyl}-2-[4-(propan-2-yl)-1H-1,2,3-triazol-1-yl]acetamide. Grades: ≥98%. CAS No. 2248003-60-1. Molecular formula: C24H26FN7O3. Mole weight: 479.51. |  |
| AZD3229 Tosylate | AZD3229 Tosylate is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. Uses: Scientific research. Group: Signaling pathways. CAS No. 2248003-71-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112802A. | |
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