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| Product | Description | |
|---|---|---|
| Azemiglitazone | Azemiglitazone (MSDC-0602) is an orally active thiazolidinedione (TZD) -like molecule, which binds to PPARγ with low binding and activating affinity. Azemiglitazone inhibits mitochondrial pyruvate carrier ( MPC ), which inhibits Alzheimers disease and diminishes nonalcoholic steatohepatitis (NASH) caused liver injury [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSDC-0602. CAS No. 1133819-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108022. |  |
| Azemiglitazone potassium | Azemiglitazone potassium (MSDC-0602K), a PPARγ -sparing thiazolidinedione (Ps-TZD), binds to PPARγ with the IC 50 of 18.25 μM [1]. Azemiglitazone potassium modulates the mitochondrial pyruvate carrier (MPC). Azemiglitazone potassium can be used for the research of fatty liver including dysfunctional lipid metabolism, inflammation, and insulin resistance [2]. Azemiglitazone potassium, an insulin sensitizer, improves insulinemia and fatty liver disease in mice, alone and in combination with Liraglutide [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSDC-0602K. CAS No. 1314533-27-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108022A. | |
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