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The enzyme, characterized from the bacterium Amycolatopsis mediterranei, is involved in biosynthesis of the antitubercular drug rifamycin B. Group: Enzymes. Synonyms: AdoMet:27-O-demethylrifamycin SV methyltransferase. Enzyme Commission Number: EC 2.1.1.315. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1923; 27-O-demethylrifamycin SV methyltransferase; EC 2.1.1.315; AdoMet:27-O-demethylrifamycin SV methyltransferase. Cat No: EXWM-1923.
3,5-dihydroxyphenylacetyl-CoA synthase
The enzyme, characterized from the bacterium Amycolatopsis mediterranei, is involved in biosynthesis of the nonproteinogenic amino acid (S)-3,5-dihydroxyphenylglycine, a component of the vancomycin-type antibiotic balhimycin. Group: Enzymes. Synonyms: DpgA. Enzyme Commission Number: EC 2.3.1.246. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2195; 3,5-dihydroxyphenylacetyl-CoA synthase; EC 2.3.1.246; DpgA. Cat No: EXWM-2195.
3-amino-5-hydroxybenzoate synthase
A pyridoxal 5'-phosphate enzyme. The enzyme from the bacterium Amycolatopsis mediterranei participates in the pathway for rifamycin B biosynthesis. The enzyme also functions as a transaminase earlier in the pathway, producing UDP-α-D-kanosamine. Group: Enzymes. Synonyms: AHBA synthase; rifK (gene name). Enzyme Commission Number: EC 4.2.1.144. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4985; 3-amino-5-hydroxybenzoate synthase; EC 4.2.1.144; AHBA synthase; rifK (gene name). Cat No: EXWM-4985.
4-hydroxymandelate oxidase
A flavoprotein (FMN). The enzyme from the bacterium Amycolatopsis orientalis is involved in the biosynthesis of L-(4-hydroxyphenyl)glycine and L-(3,5-dihydroxyphenyl)glycine, two non-proteinogenic amino acids occurring in the vancomycin group of antibiotics. Group: Enzymes. Synonyms: 4HmO; HmO. Enzyme Commission Number: EC 1.1.3.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0419; 4-hydroxymandelate oxidase; EC 1.1.3.46; 4HmO; HmO. Cat No: EXWM-0419.
alcohol dehydrogenase (nicotinoprotein)
Contains Zn2+. Nicotinoprotein alcohol dehydrogenases are unique medium-chain dehydrogenases/reductases (MDR) alcohol dehydrogenases that have a tightly bound NAD+/NADH cofactor that does not dissociate during the catalytic process. Instead, the cofactor is regenerated by a second substrate or electron carrier. While the in vivo electron acceptor is not known, N,N-dimethyl-4-nitrosoaniline (NDMA), which is reduced to 4-(hydroxylamino)-N,N-dimethylaniline, can serve this function in vitro.The enzyme from the Gram-positive bacterium Amycolatopsis methanolica can accept many primary alcohols as substrates, including benzylalcohol. Group: Enzymes. Synonyms: NDMA-dependent alcohol dehydrogenase; nicotinoprotein alcohol dehydrogenase; np-ADH; ethanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase. Enzyme Commission Number: EC 1.1.99.36. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0464; alcohol dehydrogenase (nicotinoprotein); EC 1.1.99.36; NDMA-dependent alcohol dehydrogenase; nicotinoprotein alcohol dehydrogenase; np-ADH; ethanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase. Cat No: EXWM-0464.
chloroorienticin B synthase
The enzyme from the bacterium Amycolatopsis orientalis is involved in the biosynthesis of the glycopeptide antibiotic chloroeremomycin. Group: Enzymes. Synonyms: GtfA. Enzyme Commission Number: EC 2.4.1.311. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2547; chloroorienticin B synthase; EC 2.4.1.311; GtfA. Cat No: EXWM-2547.
devancosaminyl-vancomycin vancosaminetransferase
The enzyme, isolated from the bacterium Amycolatopsis orientalis, catalyses the ultimate step in the biosynthesis of the antibiotic vancomycin. Group: Enzymes. Synonyms: devancosaminyl-vancomycin TDP-vancosaminyltransferase; GtfD; dTDP-β-L-vancomycin:desvancosaminyl-vancomycin β-L-vancosaminetransferase; desvancosaminyl-vancomycin vancosaminetransferase. Enzyme Commission Number: EC 2.4.1.322. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2559; devancosaminyl-vancomycin vancosaminetransferase; EC 2.4.1.322; devancosaminyl-vancomycin TDP-vancosaminyltransferase; GtfD; dTDP-β-L-vancomycin:desvancosaminyl-vancomycin β-L-vancosaminetransferase; desvancosaminyl-vancomycin vancosaminetransferase. Cat No: EXWM-2559.
kanosamine kinase
The enzyme from the bacterium Amycolatopsis mediterranei is specific for kanosamine. Group: Enzymes. Synonyms: rifN (gene name). Enzyme Commission Number: EC 2.7.1.179. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3010; kanosamine kinase; EC 2.7.1.179; rifN (gene name). Cat No: EXWM-3010.
(S)-3,5-dihydroxyphenylglycine transaminase
A pyridoxal-5'-phosphate protein. The enzyme from the bacterium Amycolatopsis orientalis catalyses the reaction in the reverse direction as part of the biosynthesis of the (S)-3,5-dihydroxyphenylglycine constituent of the glycopeptide antibiotic chloroeremomycin. Group: Enzymes. Synonyms: HpgT. Enzyme Commission Number: EC 2.6.1.103. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2843; (S)-3,5-dihydroxyphenylglycine transaminase; EC 2.6.1.103; HpgT. Cat No: EXWM-2843.
vancomycin aglycone glucosyltransferase
The enzyme from the bacterium Amycolatopsis orientalis is involved in the biosynthesis of the glycopeptide antibiotic chloroeremomycin. Group: Enzymes. Synonyms: GtfB (ambiguous). Enzyme Commission Number: EC 2.4.1.310. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2546; vancomycin aglycone glucosyltransferase; EC 2.4.1.310; GtfB (ambiguous). Cat No: EXWM-2546.
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