Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Bafetinib | A substituted benzamide derivative structurally related to STI-571 (Imatinib Mesylate). It was identified as highly potent Bcr-Abl kinase inhibitor. Group: Biochemicals. Alternative Names: N-[3- ([4, 5'-Bipyrimidin]-2-ylamino) -4-methylphenyl]-4-[[ (3S) -3- (dimethylamino) -1-pyrrolidinyl]methyl]-3- (trifluoromethyl) benzamide; INNO 406; NS 187. Grades: Highly Purified. CAS No. 859212-16-1. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Bafetinib | Bafetinib, also known as INNO-406, is an orally bioavailable 2-phenylaminopyrimidine derivative with potential antineoplastic activity. Bafetinib specifically binds to and inhibits the Bcr/Abl fusion protein tyrosine kinase, an abnormal enzyme produced by Philadelphia chromosomal translocation associated with chronic myeloid leukemia (CML). Synonyms: INNO406; INNO-406; INNO 406; NS187; NS-187; NS 187; Bafetinib. Grades: 0.98. CAS No. 859212-16-1. Molecular formula: C30H31F3N8O. Mole weight: 576.61. |  |
| Lyn-IN-1 | Bafetinib is a potent and selective dual Bcr-Abl/Lyn inhibitor, but it does not inhibit the phosphorylation of the T315I mutant and is less potent to PDGFR and c-Kit. It can block the autophosphorylation of Bcr-Abl and suppresses the growth of Bcr-Abl-positive leukemic cell lines including K562, KU812 and BaF3/wt. It is also highly potent to inhibit tumor growth in murine tumor models. Synonyms: INNO-406; NS-187; INNO 406; NS 187; INNO406; NS187. Grades: >98%. CAS No. 887650-05-7. Molecular formula: C30H31F3N8O. Mole weight: 576.62. | |
| N-[3- ([4, 5'-Bipyrimidin]-2-ylamino) -4-methylphenyl]-4-[[ (3S) -3- (dimethylamino) -1-pyrrolidinyl]methyl]-3- (trifluoromethyl) benzamide | N-[3- ([4, 5'-Bipyrimidin]-2-ylamino) -4-methylphenyl]-4-[[ (3S) -3- (dimethylamino) -1-pyrrolidinyl]methyl]-3- (trifluoromethyl) benzamide. Group: Biochemicals. Alternative Names: Bafetinib; INNO 406; NS 187. Grades: Highly Purified. CAS No. 859212-16-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C30H31F3N8O. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
