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Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Baloxavir acid; S-033447. CAS No. 1985605-59-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109025A.
Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration. Synonyms: Baloxavir acid; BXA; Xofluza; S-033447. Grades: ≥98%. CAS No. 1985605-59-1. Molecular formula: C24H19F2N3O4S. Mole weight: 483.49.
Baloxavir Impurity 42
Baloxavir Impurity 42. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 8-fluorodibenzo[b,e]thiepin-11(6H)-one. CAS No. 1057218-86-6. Molecular formula: C14H9FOS. Mole weight: 244.04. Catalog: APB1057218866.
Baloxavir Impurity 52
Baloxavir Impurity 52. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: dibenzo[b,e]thiepin-11(6H)-one. CAS No. 1531-77-7. Molecular formula: C14H10OS. Mole weight: 226.29. Catalog: APB1531777.
Baloxavir Impurity 54
Baloxavir Impurity 54. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 3-(benzyloxy)-4-oxo-4H-pyran-2-carboxylate. CAS No. 1332855-94-3. Molecular formula: C15H14O5. Mole weight: 274.27. Catalog: APB1332855943.
Baloxavir Impurity 61
Baloxavir Impurity 61. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 3-(benzyloxy)-4-oxo-4H-pyran-2-carboxylate. CAS No. 1332855-89-6. Molecular formula: C14H12O5. Mole weight: 260.24. Catalog: APB1332855896.
Baloxavir Impurity 76
Baloxavir Impurity 76. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-(bromomethyl)-4,5-difluorobenzoate. CAS No. 1245515-61-0. Molecular formula: C9H7BrF2O2. Mole weight: 265.05. Catalog: APB1245515610.
Baloxavir marboxil
Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration. Synonyms: S-033188; HY-109025. Grades: ≥98%. CAS No. 1985606-14-1. Molecular formula: C27H23F2N3O7S. Mole weight: 571.55.
Baloxavir marboxil
Baloxavir marboxil (S-033188) is a selective inhibitor of influenza cap-dependent endonuclease. Baloxavir marboxil, a potent antiviral agent, shows activity against influenza A and B virus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-033188; RG 6152. CAS No. 1985606-14-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-109025.
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