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| Product | Description | |
|---|---|---|
| Barasertib | Barasertib. Group: Biochemicals. Alternative Names: AZD1152-HQPA. Grades: Highly Purified. CAS No. 722544-51-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H30FN7O3. US Biological Life Sciences. |  Worldwide |
| Barasertib | Barasertib is an orally bioavailable, small-molecule, dihydrogen phosphate prodrug of the pyrazoloquinazoline Aurora kinase inhibitor AZD1152-hydroxyquinazoline pyrazol anilide (AZD1152-HQPA) with potential antineoplastic activity. Synonyms: AZD1152; AZD-1152; AZD 1152; Barasertib. CAS No. 722543-31-9. Molecular formula: C26H31FN7O6P. Mole weight: 587.54. |  |
| AZD1152-HQPA | Barasertib is a potent and highly selective inhibitor of AURKB with IC50 of 0.37 nM, acting via preventing the transfer of the phosphate group from the ATP molecule to AURKB substrates. The present study demonstrated for the first time, that AURKB inhibition interferes with early regeneration of SGs. Barasertib has been demonstrated that it is 3,700-fold greater selectivity than Aurora A. Synonyms: INH 34; AZD1152-HQPA; AZD2811. Grades: ≥98%. CAS No. 722544-51-6. Molecular formula: C26H30FN7O3. Mole weight: 507.56. | |
| AZD1152, TFA Salt | An Aurora kinase inhibitor, used to treat patients with advanced solid tumors. Group: Biochemicals. Alternative Names: 3-[[7-[3-[Ethyl[2- (phosphonooxy) ethyl]amino]propoxy]-4-quinazolinyl]amino]-N- (3-fluorophenyl) -1H-pyrazole-5-acetamide Trifluoroacetic Acid Salt; Barasertib Trifluoroacetic Acid Salt; AZD-1152 Trifluoroacetic Acid Salt. Grades: Highly Purified. CAS No. 957881-03-7. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??FN?O?P; x(C ?HF?O?), Molecular Weight: 587.54. US Biological Life Sciences. | Worldwide |
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